Mouse Anti-EPCAM Recombinant Antibody (TAB-367MZ) (CAT#: TAB-367MZ)

This product is a recombinant mouse antibody that recognizes epithelial cell adhesion molecule (EpCAM). SAS cellswere used as immunogen for the mAb generation. The affinity of the mAb for EpCAM was analyzed by surface plasmon resonance and was determined as 0.3491 nM. The antibody could induce cancer cell apoptosis using SAS and HCT116 cell lines. It also could be used to directly inhibit tumor growth in vivo.

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WB

Figure 1 Anti-Human EPCAM Antibody (TAB-367MZ) in WB

Figure 1 Anti-Human EPCAM Antibody (TAB-367MZ) in WB

Western blot analysis of TAB-367MZ was performed with EpCAM Protein, Human, Recombinant (ECD, M115T, His Tag) .

TAB-367MZ incubation concentration: 2ng/μL.
The secondary antibody: HRP-Anti-Mouse IgG (H+L)
Lane 1: Reducing Antigen (0.1μg)
Lane 2: Reducing Antigen (0.3μg)
Lane 3: Reducing Antigen (0.6μg)

ELISA

Figure 2 Anti-Human EPCAM Antibody (TAB-367MZ) in ELISA

Figure 2 Anti-Human EPCAM Antibody (TAB-367MZ) in ELISA

ELISA analysis of TAB-367MZ was performed by coating with EpCAM Protein, Human, Recombinant (ECD, M115T, His Tag).

The secondary antibody: HRP-Anti-Mouse IgG (H+L)


Specifications

  • Immunogen
  • SAS cells
  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human EpCAM (Epithelial cell adhesion molecule)
  • Species Reactivity
  • Human
  • Applications
  • FC, FuncS, Inhib, WB
  • Related Disease
  • Colon carcinoma

Product Property

  • Purity
  • >95% as determined by SDS-PAGE
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • EPCAM; epithelial cell adhesion molecule; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein)

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "EPCAM"

Immunotoxin

CAT Product Name Application Type
AGTO-L013E anti-EPCAM immunotoxin MOC31 (IgG)-PE Cytotoxicity assay, Functional assay
AGTO-L013D anti-EPCAM immunotoxin MOC31 (IgG)-DT Cytotoxicity assay, Functional assay
AGTO-L013G anti-EPCAM immunotoxin MOC31 (IgG)-Gel Cytotoxicity assay, Functional assay
AGTO-L013R anti-EPCAM immunotoxin MOC31 (IgG)-RTA Cytotoxicity assay, Functional assay
AGTO-L013O anti-EPCAM immunotoxin MOC31 (IgG)-Bouganin Cytotoxicity assay, Functional assay

Humanized Antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1163 Hi-Affi™ Rabbit Anti-EPCAM Recombinant Antibody (clone DS1163AB) IHC-P, WB, ICC, ICC, IF Rabbit IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-106 Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Adecatumumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut ADCC enhanced antibody
AFC-TAB-213 Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Tucotuzumab), ADCC Enhanced Neut, ELISA, IF, IP, FuncS ADCC enhanced antibody
AFC-TAB-701 Afuco™ Anti-EpCAM ADCC Recombinant Antibody (Edrecolomab), ADCC Enhanced ELISA, IP, FC, FuncS, IF, Neut ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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