Anti-Human EPCAM Recombinant Antibody (17-C20) (CAT#: TAB-360MZ)
This antibody that binds to Epithelial Cell Adhesion Molecule (EpCAM) shows good affinity, good cross-reactivity profiles and excellent ADCC and CDCC activity, which can be potentially used in the treatment of cancer.
Specific Inquiry
ELISA
Figure 1 shows ELISA binding analysis of 12-C15 IgG, 16-G5 IgG and 17-C20 IgG to human EpCAM-Fc.
MAXI-Sorb plates were coated with human EpCAM-Fc at a concentration of 1 μg/ml. The antibody was added in 2-fold dilutions from 133 nM to 65 pM.
ELISA
Figure 2 shows ELISA binding analysis of 3-17I scFv, 7-F17 scFv, 17- C20 scFv and 24-G6 scFv to human EpCAM-Fc.
MAXI-Sorb plates were coated with human EpCAM-Fc at a concentration of 1 μg/ml. The antibody was added in 2-fold dilutions from 133 nM to 65 pM.
ELISA
Figure 3 shows ELISA binding analysis of 3-17I scFv, 7-F17 scFv, 17- C20 scFv and 24-G6 scFv to cynomolgus EpCAM-Fc.
MAXI-Sorb plates were coated with human EpCAM-Fc at a concentration of 1 μg/ml. The antibody was added in 2-fold dilutions from 133 nM to 65 pM.
Specifications
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Species Reactivity
- Monkey
- Clone
- 17-C20
- Applications
- ELISA
- Related Disease
- Cancers such as breast, colorectal, prostate, ovary, bladder, gallbladder, pancreas, lung cancer
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- EPCAM; epithelial cell adhesion molecule; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein)
- Gene ID
- 4072
- UniProt ID
- P16422
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L013E | anti-EPCAM immunotoxin MOC31 (IgG)-PE | Cytotoxicity assay, Functional assay | |
| AGTO-L013D | anti-EPCAM immunotoxin MOC31 (IgG)-DT | Cytotoxicity assay, Functional assay | |
| AGTO-L013G | anti-EPCAM immunotoxin MOC31 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
| AGTO-L013R | anti-EPCAM immunotoxin MOC31 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
| AGTO-L013O | anti-EPCAM immunotoxin MOC31 (IgG)-Bouganin | Cytotoxicity assay, Functional assay |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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