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    Anti-Human EPCAM Recombinant Antibody (h2D11B) (CAT#: TAB-376MZ)

    This antibody h2D11B specifically binds to epithelial cell adhesion/activating molecule EpCAM expressed on cancer cells, which can induce cancer cell apoptosis. The antibody can be potentially used as diagnostic and therapeutic agents.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
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    We require custom production
    • Published Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Cyt

    Figure 1 shows effect of AbGn bsAbs on cytotoxic activity (% of cell death) in pancreatic cancer cell in the presence of human PBMC.

    Figure 1 shows effect of AbGn bsAbs on cytotoxic activity (% of cell death) in pancreatic cancer cell in the presence of human PBMC.

    Cyt

    Figure 2 shows effect of AbGn bsAbs on cytotoxic activity (% of cell death) in Multiple Myeloma cell RPMI 8266 in the presence of human PBMC.

    Figure 2 shows effect of AbGn bsAbs on cytotoxic activity (% of cell death) in Multiple Myeloma cell RPMI 8266 in the presence of human PBMC.

    Inhib

    Figure 3 shows effect of bsAbs on % of cell growth inhibition in pancreatic cancer cell in the presence of hPBMC.

    Figure 3 shows effect of bsAbs on % of cell growth inhibition in pancreatic cancer cell in the presence of hPBMC.

    Inhib

    Figure 4 shows effect of bsAbs on % of cell growth inhibition in lung cancer cell NCI-H358 in the presence of hPBMC.

    Figure 4 shows effect of bsAbs on % of cell growth inhibition in lung cancer cell NCI-H358 in the presence of hPBMC.


    Specifications

    • Host Species
    • Human
    • Type
    • Humanized antibody
    • Specificity
    • Human
    • Clone
    • h2D11B
    • Applications
    • Cyt, Inhib
    • Related Disease
    • Cancers such as breast cancer, colorectal cancer, gastric cancer, lung cancer, and prostate cancer

    Applications

    • Application Notes
    • This antibody has been reported for use in Cytotoxicity, Inhibition.

    Target

    • Alternative Names
    • EPCAM; epithelial cell adhesion molecule; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein)

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

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    See other products for "EPCAM"

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    Please select product type
    Humanized Antibodies Immunotoxins Mouse Antibodies Human Antibodies Rabbit Monoclonal Antibodies IgM Antibodies ADCC Enhanced Antibodies Fab Antibodies IgG Antibodies ScFv Antibodies MHC Tetramers for Cancer Antibody Magnetic Beads Cancer Stem Cell Biomarker Specific Antibodies ScFv-Fc Chimeras FC Reagents & Kits IHC Kits & Antibodies Extracellular Vesicle Antibodies Biparatopic Antibodies
    CAT Product Name Application Type
    TAB-213 Humanized Anti-EPCAM Recombinant Antibody (clone Tucotuzumab) WB, Neut, ELISA, IF, IP, FuncS, FC Humanized (from mouse) IgG1
    TAB-112-F(E) Anti-Human EpCAM Recombinant Antibody Fab Fragment, 17-1A (Citatuzumab Bogatox) Neut, ELISA, IF, IP, FuncS, FC, ICC Fab - G1 - kappa
    TAB-374MZ Anti-Human EPCAM Recombinant Antibody (h12H8B) FC, ELISA Humanized antibody
    TAB-375MZ Anti-Human EPCAM Recombinant Antibody (h12H8C) FuncS, Inhib Humanized antibody
    TAB-362MZ-S(P) Anti-Human EPCAM Recombinant Antibody scFv Fragment (3622W94) Confocal, ELISA Humanized antibody

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