This antibody is a recombinant monoclonal antibody Fab fragment targeting the Interleukin-2 receptor subunit alpha (IL2RA), derived from mouse. It specifically binds to human IL-2RA and can be potentially used in the research of graft versus host disease. It has been tested by Enzyme-linked immunosorbent assay and other applications.
Figure 1 Kaplan–Meier OS (left) and TRM (right) curves of corticosteroid refractory aGVHD patients treated with Inolimomab from the time of HSCT.
At 3 years: OS=54.5% (95% CI=36.3–69.6%) and TRM=29.7% (95% CI=16.6–49.6%).
Girerd, S., Renaud, M., Guilhot, J., Giraud, C., Larchee, R., Jollet, I., & Guilhot, F. (2013). Long-term follow-up of corticosteroid refractory acute GVHD treated with an Inolimomab-based algorithm: a single center experience. Bone marrow transplantation, 48(9), 1243.
Figure 2 Kaplan–Meier OS curves of the two significant prognostic factors: response to Inolimomab (left, P<0.01) and age of patient (right, P<0.05).
Girerd, S., Renaud, M., Guilhot, J., Giraud, C., Larchee, R., Jollet, I., & Guilhot, F. (2013). Long-term follow-up of corticosteroid refractory acute GVHD treated with an Inolimomab-based algorithm: a single center experience. Bone marrow transplantation, 48(9), 1243.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
IAB-B073(A) | Recombinant Anti-human IL2RA Intrabody [(D-Arg)9] | IF, ELISA, FuncS | scFv-(D-Arg)9 |
IAB-B073(G) | Recombinant Anti-human IL2RA Intrabody [+36 GFP] | IF, FC, WB, FuncS | scFv-(+36GFP) |
IAB-B073(T) | Recombinant Anti-human IL2RA Intrabody [Tat] | WB, CO-IP, FuncS | scFv-Tat |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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