Anti-human IL2RA Fab Fragment (Inolimomab) (CAT#: TAB-641LC-F(E))

This antibody is a recombinant monoclonal antibody Fab fragment targeting the Interleukin-2 receptor subunit alpha (IL2RA), derived from mouse. It specifically binds to human IL-2RA and can be potentially used in the research of graft versus host disease. It has been tested by Enzyme-linked immunosorbent assay and other applications.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA

Figure 1 Kaplan–Meier OS (left) and TRM (right) curves of corticosteroid refractory aGVHD patients treated with Inolimomab from the time of HSCT.

Figure 1 Kaplan–Meier OS (left) and TRM (right) curves of corticosteroid refractory aGVHD patients treated with Inolimomab from the time of HSCT.

At 3 years: OS=54.5% (95% CI=36.3–69.6%) and TRM=29.7% (95% CI=16.6–49.6%).

Girerd, S., Renaud, M., Guilhot, J., Giraud, C., Larchee, R., Jollet, I., & Guilhot, F. (2013). Long-term follow-up of corticosteroid refractory acute GVHD treated with an Inolimomab-based algorithm: a single center experience. Bone marrow transplantation, 48(9), 1243.

Figure 2 Kaplan–Meier OS curves of the two significant prognostic factors: response to Inolimomab (left, P<0.01) and age of patient (right, P<0.05).

Figure 2 Kaplan–Meier OS curves of the two significant prognostic factors: response to Inolimomab (left, P<0.01) and age of patient (right, P<0.05).

Girerd, S., Renaud, M., Guilhot, J., Giraud, C., Larchee, R., Jollet, I., & Guilhot, F. (2013). Long-term follow-up of corticosteroid refractory acute GVHD treated with an Inolimomab-based algorithm: a single center experience. Bone marrow transplantation, 48(9), 1243.


Specifications

  • Host Species
  • Mouse
  • Specificity
  • Human
  • Clone
  • Inolimomab
  • Applications
  • ELISA, FuncS
  • Related Disease
  • Graft versus host disease

Applications

  • Application Notes
  • The antibody was validated for Function assay. For details, refer to Published Data.

Target

  • Alternative Names
  • IL2RA; interleukin 2 receptor, alpha; p55; CD25; IL2R; TCGFR; IDDM10; interleukin-2 receptor subunit alpha; TAC antigen; IL-2R subunit alpha; IL-2 receptor subunit alpha

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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