After reconstitution, how stable is the Human Anti-CD19 Recombinant Antibody (clone 11) Fab Fragment?

Once reconstituted, the Human Anti-CD19 Recombinant Antibody (clone 11) Fab Fragment remains stable for up to two weeks when stored at 4°C. For longer storage, aliquots should be kept at -20°C or below.

What enables the particular recognition of CD19 by the Human Anti-CD19 Recombinant Antibody (clone 11) Fab Fragment?

High specificity and little cross-reactivity with other proteins are ensured by the special variable region in the Fab portion of the Human Anti-CD19 Recombinant Antibody, which is particularly designed to attach to the extracellular domain of the CD19 molecule.

Is GLP (Good Laboratory Practices) followed in the manufacturing of the Human Anti-CD19 Recombinant Antibody (clone 11) Fab Fragment?

Yes, the fabrication and quality control processes adhere to GLP standards, ensuring high quality, reproducibility, and reliability suitable for research applications and therapeutic development.

Human Anti-CD19 Recombinant Antibody Fab Fragment (HPAB-0219-FY-F(E))

CAT#: HPAB-0219-FY-F(E)

Recombinant Fab fragment to CD19. This product is a recombinant Humanized antibody that recognizes Human CD19. The monoclonal antibody reacts with the epitope of CD19.

Gene Expression

Normal Tissue Figure 1 Colon

Mucosal lymphoid cells
Staining:Medium
Intensity: Strong
Quantity: <25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_7_3.jpg

Normal Tissue Figure 2 Testis

Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_5_6.jpg

Normal Tissue Figure 3 Appendix

Germinal center cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_2_2.jpg

Normal Tissue Figure 4 Lymph node

Germinal center cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_9_8.jpg

RNA Expression Figure 5 RNA cell line category: Cell line enhanced (Daudi, REH, U-698)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000177455-CD19

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Specifications

Host Species
Human

Derivation
Humanized

Type
Humanized Fab

Specificity
Human CD19

Species Reactivity
Human

Applications
ELISA

Related Disease
Cancer

Product Property

Purity
>95% as determined by SDS-PAGE and HPLC analysis

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
CD19 Molecule; B-Lymphocyte Surface Antigen B4; T-Cell Surface Antigen Leu-12; Differentiation Antigen CD19; CD19 Antigen; B-Lymphocyte Antigen CD19; CVID3; B4

Gene ID
930

UniProt ID
P15391

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Breast cancer biomarkers at key points during disease progression

Excellent specificity

The Human Anti-CD19 Recombinant Antibody (clone 11) Fab Fragment has shown excellent specificity in our immunoassays, providing clear and distinct labeling of CD19-positive cells with minimal background staining.

Effective in signaling studies

We used this antibody in signaling pathway studies, and it provided clear insights into CD19-mediated processes. The results were reproducible and highly informative.

High purity

The purity of this Fab fragment is impressive. SDS-PAGE confirmed it exceeded 95%, and it performs exceptionally well in all our assays without any issues.

Q&As

After reconstitution, how stable is the Human Anti-CD19 Recombinant Antibody (clone 11) Fab Fragment?

A: Once reconstituted, the Human Anti-CD19 Recombinant Antibody (clone 11) Fab Fragment remains stable for up to two weeks when stored at 4°C. For longer storage, aliquots should be kept at -20°C or below.
What enables the particular recognition of CD19 by the Human Anti-CD19 Recombinant Antibody (clone 11) Fab Fragment?

A: High specificity and little cross-reactivity with other proteins are ensured by the special variable region in the Fab portion of the Human Anti-CD19 Recombinant Antibody, which is particularly designed to attach to the extracellular domain of the CD19 molecule.
Is GLP (Good Laboratory Practices) followed in the manufacturing of the Human Anti-CD19 Recombinant Antibody (clone 11) Fab Fragment?

A: Yes, the fabrication and quality control processes adhere to GLP standards, ensuring high quality, reproducibility, and reliability suitable for research applications and therapeutic development.

View the frequently asked questions answered by Creative Biolabs Support.

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Related Diseases

Primary Immunodeficiency

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-0219-FY-F(E).pdf

MSDS

MSDS - HPAB-0219-FY-F(E).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

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