Human Anti-CD40 Recombinant Antibody (clone 2105) (CAT#: HPAB-1275WJ)
This product is a human antibody targeting human CD40, This antibody is useful for increasing or decreasing a CD40 activity in order to alter CD40 activity in vivo.
Specific Inquiry
ELISA
Figure 1 Illustrates binding of the anti-CD40 antibodies to the CD40 mutant.
ELISA
Figure 2 Anti-CD40 antibodies binds to the CD40 mutant.
CMCD
Figure 3 Shows a diagram indicating that the G2/4 antibody has a lower complement activity when the human complement is used.
FC
Figure 4 Shows diagrams indicating that conversion of the subclass of the 2105 antibody from IgG2 into different subclasses has no effect on its binding to Ramos cells.
Specifications
- Immunogen
- CD40-expressing EL-4 cells
- Host Species
- Human
- Type
- Human IgG
- Specificity
- Human CD40
- Species Reactivity
- Human
- Clone
- 2105
- Applications
- ELISA, CMCD, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The CD40 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Complement Mediated Cell Depletion, Flow Cytometry.
Target
Related Resources
Asthma
Systemic Lupus Erythematosus
Primary Immunodeficiency
Allograft Rejection
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G079E | Anti-CD40 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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