Human Anti-CD40 Recombinant Antibody (clone hsPPAT-071-04) (CAT#: HPAB-0086-WJ)
This product is a humanized IgG1 kappa antibody derived from murine PPAT-071-04 antibody, targeting human soluble CD40 (aa 1 to 173). This antibody has the same characteristics as the original murine antibody.
Specific Inquiry
FuncS
Figure 1 The anti-tumor effect in the tumor-bearing mouse model of Ramos cell by humanized antibody hsPPAT-071-04.
ADCC
Figure 2 ADCC activity with respect to T24 cell of humanized antibody hsPPAT-071-04 which used the mouse | mouth bone marrow cell.
Specifications
- Immunogen
- Full length of human CD40
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG1, κ
- Specificity
- Human CD40
- Species Reactivity
- Human
- Clone
- hsPPAT-071-04
- Applications
- ELISA, ADCC, FuncS
- Related Disease
- Acute lymphocytic leukemia, chronic leukemia, lymphomas
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in ADCC and Functional Assay.
Target
- Alternative Names
- CD40; CD40 Molecule, TNF Receptor Superfamily Member 5; CD40 Antigen (TNF Receptor Superfamily Member 5); CDW40; P50; Bp50; B Cell-Associated Molecule; CD40 Antigen
- Gene ID
- 958
- UniProt ID
- P25942
Related Resources
Asthma
Systemic Lupus Erythematosus
Primary Immunodeficiency
Allograft Rejection
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Flow Cytometry (FC) related Products
ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-262 | Anti-Human CD40 Recombinant Antibody (TAB-262) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 |
| TAB-188LC | Anti-Human CD40 Recombinant Antibody (chi220) | SPR, ELISA, Inhib, FuncS | Chimeric antibody (mouse/human) |
| TAB-202LC | Anti-CD40 Recombinant Antibody (TAB-202LC) | ELISA, FC, FuncS | Chimeric (mouse/rhesus) IgG1 |
| TAB-203LC | Anti-CD40 Recombinant Antibody (TAB-203LC) | ELISA, FC, FuncS | Chimeric (mouse/rhesus) IgG4 |
| TAB-188LC-F(E) | Anti-Human CD40 Recombinant Antibody Fab Fragment (chi220) | SPR, ELISA | Chimeric antibody (mouse/human) |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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