Human Anti-CD40 Recombinant Antibody (clone hsPPAT-071-04) (CAT#: HPAB-0086-WJ)
This product is a humanized IgG1 kappa antibody derived from murine PPAT-071-04 antibody, targeting human soluble CD40 (aa 1 to 173). This antibody has the same characteristics as the original murine antibody.
Specific Inquiry
FuncS
Figure 1 The anti-tumor effect in the tumor-bearing mouse model of Ramos cell by humanized antibody hsPPAT-071-04.
ADCC
Figure 2 ADCC activity with respect to T24 cell of humanized antibody hsPPAT-071-04 which used the mouse | mouth bone marrow cell.
Specifications
- Immunogen
- Full length of human CD40
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG1, κ
- Specificity
- Human CD40
- Species Reactivity
- Human
- Clone
- hsPPAT-071-04
- Applications
- ELISA, ADCC, FuncS
- Related Disease
- Acute lymphocytic leukemia, chronic leukemia, lymphomas
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in ADCC and Functional Assay.
Target
- Alternative Names
- CD40; CD40 Molecule, TNF Receptor Superfamily Member 5; CD40 Antigen (TNF Receptor Superfamily Member 5); CDW40; P50; Bp50; B Cell-Associated Molecule; CD40 Antigen
- Gene ID
- 958
- UniProt ID
- P25942
Related Resources
Asthma
Systemic Lupus Erythematosus
Primary Immunodeficiency
Allograft Rejection
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone hsPPAT-071-04"
See other products for "CD40"
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-759 | Anti-CD40 Recombinant Antibody (Lucatumumab) | ELISA, FC, IP, FuncS, IF, Neut, IHC | IgG1 - kappa |
| TAB-195LC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-195LC-S(P)) | ELISA | Human scFv |
| TAB-196LC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-196LC-S(P)) | ELISA | Human scFv |
| TAB-006ML | Anti-Human CD40 Recombinant Antibody (Bleselumab) | ELISA, IHC, FC, IP, IF, Inhib | IgG4, κ |
| TAB-470CQ | Anti-Human CD40 Recombinant Antibody (Selicrelumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, κ |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G079E | Anti-CD40 immunotoxin G28-5 (scFv)-PE | Cytotoxicity assay, Function study |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-189LC | Anti-Human CD40 Recombinant Antibody (F4) | SPR, ELISA | Humanized antibody |
| TAB-190LC | Anti-Human CD40 Recombinant Antibody (L3.17) | SPR, ELISA | Humanized antibody |
| TAB-194LC | Human Anti-CD40 Recombinant Antibody (TAB-194LC) | ELISA | Humanized IgG1, κ |
| TAB-200LC | Human Anti-CD40 Recombinant Antibody (TAB-200LC) | ELISA | Human IgG1, κ |
| TAB-204LC | Human Anti-CD40 Recombinant Antibody (TAB-204LC) | SPR, ELISA | Human IgG |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-202LC | Anti-CD40 Recombinant Antibody (TAB-202LC) | ELISA, FC, FuncS | Chimeric (mouse/rhesus) IgG1 |
| TAB-203LC | Anti-CD40 Recombinant Antibody (TAB-203LC) | ELISA, FC, FuncS | Chimeric (mouse/rhesus) IgG4 |
| TAB-188LC-S(P) | Anti-Human CD40 Recombinant Antibody scFv Fragment (chi220) | SPR, ELISA | Chimeric antibody (mouse/human) |
| TAB-202LC-S(P) | Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-202LC-S(P)) | FC, ELISA | scFv |
| TAB-188LC-F(E) | Anti-Human CD40 Recombinant Antibody Fab Fragment (chi220) | SPR, ELISA | Chimeric antibody (mouse/human) |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-191LC-S(P) | Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-191LC-S(P)) | ELISA | Mouse scFv |
| TAB-191LC-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-191LC-F(E)) | ELISA | Mouse Fab |
| TAB-199LC-F(E) | Rat Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-199LC-F(E)) | ELISA | Rat Fab |
| TAB-201LC-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-201LC-F(E)) | FC, ELISA | Mouse Fab |
| TAB-207LC-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-207LC-F(E)) | ELISA | Mouse Fab |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-362CQ | Human Anti-CD40 Recombinant Antibody (clone 5D12) | Block, ELISA, FC, SPR, IP, IHC | Human IgG4, κ |
| NEUT-363CQ | Mouse Anti-CD40 Recombinant Antibody (clone 5C3) | FC, Block, Activ | Mouse IgG1, κ |
| NEUT-365CQ | Hamster Anti-CD40 Recombinant Antibody (clone HM40-3) | FC, Block, Costim, IHC | Hamster IgM |
| NEUT-366CQ | Rat Anti-CD40 Recombinant Antibody (clone MAB0819) | Block, Activ | Rat IgG2 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-364CQ | Mouse Anti-CD40 Recombinant Antibody (clone CBL829) | WB, Neut | Mouse IgG2b, κ |
| NEUT-367CQ | Mouse Anti-CD40 Recombinant Antibody (clone CBL013) | WB, IHC, Neut | Mouse IgG2 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4059 | Hi-Affi™ Rabbit Anti-CD40 Recombinant Antibody (clone SI126DS) | ELISA | Rabbit IgG |
Agonistic Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-105LC | Human Anti-CD40 Recombinant Antibody (MOB-105LC) | FC, FuncS | Human IgG1, κ |
| MOB-106LC | Human Anti-CD40 Recombinant Antibody (MOB-106LC) | FC, FuncS, ELISA | Human IgG2, κ |
| MOB-107LC | Human Anti-CD40 Recombinant Antibody (MOB-107LC) | FC, FuncS, ELISA | Human IgG2, κ |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0162-YC | Human Anti-CD40 Recombinant Antibody (HPAB-0162-YC) | FC | Human IgG |
| HPAB-0163-YC | Human Anti-CD40 Recombinant Antibody (HPAB-0163-YC) | FC | Human IgG |
| MOB-119CQ | Human Anti-CD40 Recombinant Antibody (MOB-119CQ) | ELISA, IHC, IF, IP, FC, FuncS | Human IgG2, κ |
| MOB-120CQ | Human Anti-CD40 Recombinant Antibody (clone Chi Lob 7/4) | ELISA, IHC, IF, IP, FC, FuncS | Human IgG1 |
| MOB-022LC | Rat Anti-CD40 Recombinant Antibody (clone CBLS-210) | ELISA, FuncS | Rat IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0162-YC-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-0162-YC-F(E)) | FC | Human Fab |
| HPAB-0163-YC-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-0163-YC-F(E)) | FC | Human Fab |
| HPAB-0164-YC-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-0164-YC-F(E)) | FC, Agonist | Human Fab |
| HPAB-0165-YC-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-0165-YC-F(E)) | FC | Human Fab |
| HPAB-0166-YC-F(E) | Human Anti-CD40 Recombinant Antibody (clone S2C6); Fab Fragment | FC, FuncS | Human Fab |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-021CN | Human Anti-CD40 Recombinant Antibody (NS-021CN) | ELISA, IF, Block, FuncS | Human IgG |
| NS-021CN-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (NS-021CN-F(E)) | ELISA | Human Fab |
| NS-021CN-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (NS-021CN-S(P)) | ELISA | Human scFv |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-152 | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Dacetuzumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-262 | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Teneliximab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
| AFC-TAB-759 | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Lucatumumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-470CQ | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Selicrelumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-006ML | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Bleselumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0086-WJ-S(P) | Human Anti-CD40 Recombinant Antibody (clone hsPPAT-071-04); scFv Fragment | ELISA | Humanized scFv |
| HPAB-0386-FY-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (HPAB-0386-FY-S(P)) | Activ, IF | Human scFv |
| HPAB-1272WJ-S(P) | Human Anti-CD40 Recombinant Antibody (clone F2-103); scFv Fragment | ELISA, WB | Human scFv |
| HPAB-1833-FY-F(E) | Human Anti-CD40 Recombinant Antibody (clone 3.1.1); scFv Fragment | Activ | Human scFv |
| HPAB-1834-FY-F(E) | Human Anti-CD40 Recombinant Antibody (clone 21.4.1); scFv Fragment | Agonist, Activ | Human scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1218WJ | Recombinant Llama Anti-CD40 Single Domain Antibody (CD40-1) | ELISA | Llama VHH |
| HPAB-1219WJ | Recombinant Llama Anti-CD40 Single Domain Antibody (CD40-2) | ELISA | Llama VHH |
| HPAB-1220WJ | Recombinant Llama Anti-CD40 Single Domain Antibody (CD40-3) | ELISA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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