Afuco™ Anti-CD70 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H76) (CAT#: AFC-TAB-H76)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant Humanized (from mouse) antibody to Human CD70. It is a monoclonal antibody designed for the treatment of cancer.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1486_B2_3_selected.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1486_B2_3_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1559_D6_2_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1559_D6_2_red_green.jpg
Figure 3 RNA cell line category: Cell line enhanced (SiHa, THP-1, U-251 MG, U-266/70, U-266/84, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125726-CD70
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125726-CD70
Specifications
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Specificity
- CD70 (tumor necrosis factor superfamily member 7, TNFSF7, CD27LG, CD27L) [Homo sapiens]
- Species Reactivity
- Human
- Applications
- ELISA, FC, IP, FuncS, IF, Neut
- Conjugate
- Unconjugated
- Generic Name
- Vorsetuzumab
- Related Disease
- Autoimmune diseases
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD70; CD70 molecule; CD27LG, TNFSF7, tumor necrosis factor (ligand) superfamily, member 7; CD70 antigen; CD27L; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7;
- Gene ID
- 970
- UniProt ID
- P32970
Related Resources
Please refer to Vorsetuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Vorsetuzumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "vorsetuzumab"
Anti-Human CD70 Recombinant Antibody (Vorsetuzumab)Recombinant Humanized (from mouse) antibody to Human CD70. Vorsetuzumab is a monoclonal antibody designed for the treatment of cancer.
See other products for "CD70"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1584z | Mouse Anti-CD70 Recombinant Antibody (clone 24B8) | FC, IF, IHC, IP | Mouse IgG1, κ |
| MOB-072LC | Human Anti-CD70 Recombinant Antibody (MOB-072LC) | ELISA, FC, FuncS | Human IgG |
| MOB-073LC | Mouse Anti-CD70 Recombinant Antibody (clone hCD70.21) | ELISA, FC, FuncS | Mouse IgG |
| FAMAB-1735CQ | Mouse Anti-CD70 Recombinant Antibody (clone TAN 1-7) | Block, ELISA, FC, IF | Mouse IgG2a |
| VS-0723-WK186 | Rabbit Anti-CD70 Recombinant Antibody (VS-0723-WK186) | ELISA, FC | Rabbit IgG |
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