Afuco™ Anti-CD80 ADCC Recombinant Antibody (Galiximab), ADCC Enhanced (CAT#: AFC-TAB-215)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD8. Galiximab is a monoclonal antibody designed for the treatment of B-cell lymphoma. As of September 2009, The drug is a chimeric antibody from Macaca irus and Homo sapiens.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Bone marrow
(Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25368/56116_B_6_4.jpg
(Hematopoietic cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25368/56116_B_6_4.jpg
Figure 2 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25368/56076_A_9_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25368/56076_A_9_8.jpg
Figure 3 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, Karpas-707, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121594-CD80
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121594-CD80
Figure 3 RNA cell line category: Cell line enhanced (Daudi, HDLM-2, Karpas-707, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121594-CD80
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000121594-CD80
Specifications
- Immunogen
- CD80-transfected CHO cell line.
- Host Species
- Primate
- Derivation
- Chimeric (primate/human)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Galiximab
- Applications
- ELISA, FC, IP, FuncS, IF
- Conjugate
- Unconjugated
- Generic Name
- Galiximab
- Related Disease
- Non-Hodgkin's lymphoma (NHL)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Galiximab; 357613-77-5; IDEC-114; 16C10; CD80; CD80 molecule; CD28LG, CD28LG1, CD80 antigen (CD28 antigen ligand 1, B7 1 antigen), CD80 molecule; T-lymphocyte activation antigen CD80; B lymphocyte activation antigen B7; B7 1; B7.1; activation B7-1 antigen;
- Gene ID
- 941
- UniProt ID
- P33681
Related Resources
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Allograft Rejection
Autoimmune Thyroid Disease
Graft-versus-Host Disease
Maturity Onset Diabetes of the Young
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Galiximab"
Anti-Human CD80 Recombinant Antibody (Galiximab)Recombinant monoclonal antibody to CD8. Galiximab is a monoclonal antibody designed for the treatment of B-cell lymphoma. As of September 2009, The drug is a chimeric antibody from Macaca irus and Homo sapiens.
See other products for "CD80"
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-215 | Anti-Human CD80 Recombinant Antibody (Galiximab) | WB, ELISA, FC, IP, FuncS, IF, Neut | IgG1 - lambda |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L001G | anti-CD80 immunotoxin 6G7 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
| AGTO-L001S | anti-CD80 immunotoxin 6G7 (IgG)-Sap | Cytotoxicity assay, Functional assay | |
| AGTO-L001O | anti-CD80 immunotoxin 6G7 (IgG)-Bouganin | Cytotoxicity assay, Functional assay |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-347LC | Mouse Anti-CD80 Recombinant Antibody (TAB-347LC) | FC | Mouse IgG |
| TAB-347LC-S(P) | Mouse Anti-CD80 Recombinant Antibody; scFv Fragment (TAB-347LC-S(P)) | FC | Mouse scFv |
| TAB-347LC-F(E) | Mouse Anti-CD80 Recombinant Antibody; Fab Fragment (TAB-347LC-F(E)) | FC | Mouse Fab |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-159LC | Recombinant Anti-Human CD80 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (primate/human) |
Low- or Non-fucosylated Oligosaccharide
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-159LC-1 | Recombinant Anti-Human CD80 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (primate/human) |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0066MZ | Chicken Anti-BB1 Polyclonal IgY | WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-409CQ | Mouse Anti-CD80 Recombinant Antibody (clone CBL764) | FC, IHC, CyTOF®, ELISA, Neut | Mouse IgG1 |
| NEUT-410CQ | Mouse Anti-CD80 Recombinant Antibody (clone 6N36) | FC, IHC, Neut, WB | Mouse IgG1 |
| NEUT-411CQ | Mouse Anti-CD80 Recombinant Antibody (clone AS29) | IP, Neut | Mouse IgG1 |
| NEUT-412CQ | Mouse Anti-CD80 Recombinant Antibody (VMC172) | Neut, FC | Mouse IgG1 |
| NEUT-415CQ | Hamster Anti-Cd80 Recombinant Antibody (clone 16-10A1) | FC, FuncS, Neut, IHC, IHC-Fr | Hamster IgG |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-413CQ | Rat Anti-Cd80 Recombinant Antibody (clone 1G10) | IP, Block | Rat IgG2a, κ |
| NEUT-414CQ | Hamster Anti-Cd80 Recombinant Antibody (clone MAB0826) | Block, FC, IHC-Fr | Hamster IgG |
| NEUT-416CQ | Mouse Anti-Cd80 Recombinant Antibody (clone 3H5) | Block, FC | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0583 | Hi-Affi™ Rabbit Anti-CD80 Recombinant Antibody (clone DS583AB) | WB, IHC | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-0318-CN | Rabbit Anti-CD80 Recombinant Antibody (clone JF100-4) | WB, IHC | Rabbit IgG |
| MRO-0319-CN | Mouse Anti-CD80 Recombinant Antibody (clone 8-E5) | WB, IF, IHC, FC | Mouse IgG2b |
| MRO-1762-CN | Rabbit Anti-CD80 Polyclonal Antibody (MRO-1762-CN) | WB, IF, IHC, FC | Rabbit IgG |
| FN-040CQ | Mouse Anti-CD80 Recombinant Antibody (clone BB1) | FC, ELISA, WB, Block | Mouse IgM, κ |
| FN-057CQ | Mouse Anti-CD80 Recombinant Antibody (clone P1.H1.A1.A1) | FC, ELISA, FuncS | Mouse IgG1 |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0063-YJ-S(P) | Human Anti-CD80 Recombinant Antibody (clone hu1F1); scFv Fragment | ELISA, FuncS | Humanized scFv |
| HPAB-0708-FY-F(E) | Mouse Anti-CD80 Recombinant Antibody (clone AB007); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1587WJ-S(P) | Mouse Anti-CD80 Recombinant Antibody; scFv Fragment (clone 1F1) | ELISA, WB | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0063-YJ-F(E) | Human Anti-CD80 Recombinant Antibody (clone hu1F1); Fab Fragment | ELISA, FuncS | Humanized Fab |
| HPAB-0708-FY-S(P) | Mouse Anti-CD80 Recombinant Antibody (clone AB007); Fab Fragment | ELISA | Mouse Fab |
| HPAB-1587WJ-F(E) | Mouse Anti-CD80 Recombinant Antibody; Fab Fragment (clone 1F1) | ELISA, WB | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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