This product is a recombinant humanized antibody that recognizes human B7-1. Mab hu1F1 functions in treatments for various autoimmune diseases, transplant rejection, inflammatory disorders, and infectious diseases.
Figure 1 Tumor necrosis factor-a stimulated porcine splenocytes activates human T cells
The activation was inhibited by addition of antihuman B7 antibodies, which cross-reacts with pig CD80. hu1F1, cross-reactive antihCD80; mu4B2, non-crossreactive antihCD80; CTLA4-Ig; 9.3-Fab fragment, antihCD28.
Tadaki, D. K., Williams, A., Lee, K. P., Kirk, A. D., & Harlan, D. M. (2003). Porcine CD80: cloning, characterization, and evidence for its role in direct human T‐cell activation. Xenotransplantation, 10(3), 252-258.
Figure 2 a graph depicting the results of a competitive binding assay.
The graph depicts the results of a competitive binding assay of murine or humanized anti-human B7-1 mAbs to CHO transfected with rhB7-1 (CHO/hB7-1). Increasing concentrations of unlabeled competitor antibodies were incubated with CHO/hB7-1 cells in the presence of radiolabeled tracer humanized 1F1, and the ratio of bound/ free antibody was determined.
Vasquez, M., Carreno, B., Celniker, A. C., Collins, M., Goldman, S., Gray, G. S., ... & Veldman, G. M. (2005). U.S. Patent No. 6, 913, 747. Washington, DC: U.S. Patent and Trademark Office.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1234z | Mouse Anti-CD80 Recombinant Antibody (clone 31G9) | WB, FC, IHC | Mouse IgG2b, κ |
MOB-0490CT | Recombinant Mouse anti-Human CD80 Monoclonal antibody (NFN-344) | FC | |
MRO-0318-CN | Rabbit Anti-CD80 Recombinant Antibody (clone JF100-4) | WB, IHC | Rabbit IgG |
MRO-0319-CN | Mouse Anti-CD80 Recombinant Antibody (clone 8-E5) | WB, IF, IHC, FC | Mouse IgG2b |
VS3-CJ882 | Mouse Anti-CD80 Recombinant Antibody (clone 2D10.4) | IF, FC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-215 | Anti-Human CD80 Recombinant Antibody (Galiximab) | WB, ELISA, FC, IP, FuncS, IF, Neut | IgG1 - lambda |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L001G | anti-CD80 immunotoxin 6G7 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
AGTO-L001S | anti-CD80 immunotoxin 6G7 (IgG)-Sap | Cytotoxicity assay, Functional assay | |
AGTO-L001O | anti-CD80 immunotoxin 6G7 (IgG)-Bouganin | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-347LC | Mouse Anti-CD80 Recombinant Antibody (TAB-347LC) | FC | Mouse IgG |
TAB-347LC-S(P) | Mouse Anti-CD80 Recombinant Antibody; scFv Fragment (TAB-347LC-S(P)) | FC | Mouse scFv |
TAB-347LC-F(E) | Mouse Anti-CD80 Recombinant Antibody; Fab Fragment (TAB-347LC-F(E)) | FC | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-159LC | Recombinant Anti-Human CD80 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (primate/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
Gly-159LC-1 | Recombinant Anti-Human CD80 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (primate/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0066MZ | Chicken Anti-BB1 Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-409CQ | Mouse Anti-CD80 Recombinant Antibody (clone CBL764) | FC, IHC, CyTOF®, ELISA, Neut | Mouse IgG1 |
NEUT-410CQ | Mouse Anti-CD80 Recombinant Antibody (clone 6N36) | FC, IHC, Neut, WB | Mouse IgG1 |
NEUT-411CQ | Mouse Anti-CD80 Recombinant Antibody (clone AS29) | IP, Neut | Mouse IgG1 |
NEUT-412CQ | Mouse Anti-CD80 Recombinant Antibody (VMC172) | Neut, FC | Mouse IgG1 |
NEUT-415CQ | Hamster Anti-Cd80 Recombinant Antibody (clone 16-10A1) | FC, FuncS, Neut, IHC, IHC-Fr | Hamster IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-413CQ | Rat Anti-Cd80 Recombinant Antibody (clone 1G10) | IP, Block | Rat IgG2a, κ |
NEUT-414CQ | Hamster Anti-Cd80 Recombinant Antibody (clone MAB0826) | Block, FC, IHC-Fr | Hamster IgG |
NEUT-416CQ | Mouse Anti-Cd80 Recombinant Antibody (clone 3H5) | Block, FC | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-0583 | Hi-Affi™ Rabbit Anti-CD80 Recombinant Antibody (clone DS583AB) | WB, IHC | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-215 | Afuco™ Anti-CD80 ADCC Recombinant Antibody (Galiximab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0063-YJ-S(P) | Human Anti-CD80 Recombinant Antibody (clone hu1F1); scFv Fragment | ELISA, FuncS | Humanized scFv |
HPAB-0708-FY-F(E) | Mouse Anti-CD80 Recombinant Antibody (clone AB007); scFv Fragment | ELISA | Mouse scFv |
HPAB-1587WJ-S(P) | Mouse Anti-CD80 Recombinant Antibody; scFv Fragment (clone 1F1) | ELISA, WB | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0063-YJ-F(E) | Human Anti-CD80 Recombinant Antibody (clone hu1F1); Fab Fragment | ELISA, FuncS | Humanized Fab |
HPAB-0708-FY-S(P) | Mouse Anti-CD80 Recombinant Antibody (clone AB007); Fab Fragment | ELISA | Mouse Fab |
HPAB-1587WJ-F(E) | Mouse Anti-CD80 Recombinant Antibody; Fab Fragment (clone 1F1) | ELISA, WB | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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