Human Anti-CD80 Recombinant Antibody (clone hu1F1) (CAT#: HPAB-0063-YJ)
This product is a recombinant humanized antibody that recognizes human B7-1. Mab hu1F1 functions in treatments for various autoimmune diseases, transplant rejection, inflammatory disorders, and infectious diseases.
Specific Inquiry
ELISA
Figure 2 a graph depicting the results of a competitive binding assay.
The graph depicts the results of a competitive binding assay of murine or humanized anti-human B7-1 mAbs to CHO transfected with rhB7-1 (CHO/hB7-1). Increasing concentrations of unlabeled competitor antibodies were incubated with CHO/hB7-1 cells in the presence of radiolabeled tracer humanized 1F1, and the ratio of bound/ free antibody was determined.
Vasquez, M., Carreno, B., Celniker, A. C., Collins, M., Goldman, S., Gray, G. S., ... & Veldman, G. M. (2005). U.S. Patent No. 6, 913, 747. Washington, DC: U.S. Patent and Trademark Office.
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized IgG4, κ
- Specificity
- Human CD80
- Species Reactivity
- Human
- Clone
- hu1F1
- Applications
- ELISA, FuncS
- Related Disease
- Autoimmune Diseases, Transplant Rejection, Inflammatory Disorders, Infectious Diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The antibody hu1F1 has been reported in applications of Enzyme-linked Immunosorbent Assay, Inhibition, Functional Assay. It's recommended that the optimal antibody concentration, dilution, incubition time etc. be carefully titrated in specific assays.
Target
- Alternative Names
- CD80 Molecule; CD80 Antigen (CD28 Antigen Ligand 1, B7-1 Antigen); B-Lymphocyte Activation Antigen B7; CTLA-4 Counter-Receptor B7.1; Activation B7-1 Antigen; CD28LG1; CD28LG; LAB7; BB1; h1F1; hu1F1; humanized 1F1
- Gene ID
- 941
- UniProt ID
- P33681
Related Resources
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Allograft Rejection
Autoimmune Thyroid Disease
Graft-versus-Host Disease
Maturity Onset Diabetes of the Young
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Flow Cytometry (FC) related Reagents and Kits: Empowering Cell Function Research
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-215 | Anti-Human CD80 Recombinant Antibody (Galiximab) | WB, ELISA, FC, IP, FuncS, IF, Neut | IgG1 - lambda |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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