Mouse Anti-ERBB3 Recombinant Antibody (clone 205.10.1) (CAT#: HPAB-0200-WJ)
This product is a mouse antibody targeting human HER3. This antibody shows a competitive binding with the ligand Heregulin (HRG) to HER3.
Specific Inquiry
IHC
Figure 1 The levels of p-HER3 was determined by IHC.
Tumor volumes are expressed as Mean ± S.D.
Wang, Q., Zhang, X., Shen, E., Gao, J., Cao, F., Wang, X., ... & Wang, J. (2016). The anti-HER3 antibody in combination with trastuzumab exerts synergistic antitumor activity in HER2-positive gastric cancer. Cancer Letters , 380 (1), 20-30.
WB
Figure 2 Antitumor effects in three HER2-negative gastric cancer PDXs.
Tumor specimens of PDX 5 were harvested after the end of treatment followed by analysis of lysates for p-AKT, p-ERK and p-S6.
Wang, Q., Zhang, X., Shen, E., Gao, J., Cao, F., Wang, X., ... & Wang, J. (2016). The anti-HER3 antibody in combination with trastuzumab exerts synergistic antitumor activity in HER2-positive gastric cancer. Cancer Letters , 380 (1), 20-30.
Specifications
- Immunogen
- hHER3-ECD
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human HER3
- Species Reactivity
- Human
- Clone
- 205.10.1
- Applications
- IHC, WB
- Related Disease
- Breast cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The HER3 antibody has been reported in applications of Immunohistochemistry, Western Blot.
Target
- Alternative Names
- ERBB3; erb-b2 receptor tyrosine kinase 3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1
- Gene ID
- 2065
- UniProt ID
- P21860
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
ErbB Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 205.10.1"
See other products for "ERBB3"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1729-sdAb | Recombinant Anti-human ERBB3 VHH Single Domain Antibody | WB, ICC, ChiP, FA, ELISA | Llama VHH |
| TAB-070CT | Llama Anti-ERBB3 Recombinant Single Domain Antibody (TAB-070CT) | FC, Block | Llama VHH |
| PABC-556 | Recombinant Llama Anti-ERBB3 Single Domain Antibody (BCD090-M2) | ELISA, SPR | Llama VHH |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H21 | Anti-Human ERBB3 Recombinant Antibody (Duligotuzumab) | FC, IP, ELISA, Neut, FuncS, IF, WB | Human IgG |
| TAB-244CL | Anti-Human ERBB3 Recombinant Antibody (LJM716) | WB, ELISA | Antibody |
| TAB-0033CL | Human Anti-ERBB3 Recombinant Antibody (TAB-0033CL) | ELISA, FuncS, Inhib, FC | Human IgG |
| TAB-0034CL | Human Anti-ERBB3 Recombinant Antibody (TAB-0034CL) | ELISA, FuncS, Inhib, FC | Human IgG |
| TAB-0035CL | Human Anti-ERBB3 Recombinant Antibody (TAB-0035CL) | ELISA, FuncS, Inhib, FC | Human IgG |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-H22 | Anti-Human ERBB3 Recombinant Antibody (Duligotuzumab) (TAB-H22) | ELISA, IP, FC, FuncS, Neut, IF, ICC | IgG1 - kappa |
| TAB-057CT | Human Anti-ERBB3 Recombinant Antibody (TAB-057CT) | Inhibion, ELISA | Humanized antibody |
| TAB-063CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-063CT-S(P)) | ELISA, Inhib, FC | Human scFv |
| TAB-059CT-F(E) | Anti-Human HER3 Recombinant Antibody Fab Fragment (LMAb3) | WB, ELISA, Inhibition, FC | Humanized antibody |
| TAB-063CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-063CT-F(E)) | ELISA, Inhib, FC | Humanized Fab |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L074E | HRGβ2-PE immunotoxin | Cytotoxicity assay, Functional assay |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-086 | Human Anti-ERBB3 Recombinant Antibody (clone KTN3379) | ELISA, WB, IF, FuncS | Human IgG |
| PABL-127 | Human Anti-ERBB3 Recombinant Antibody (PABL-127) | ELISA, WB, FuncS | Human IgG |
| PABL-128 | Mouse Anti-ERBB3 Recombinant Antibody (PABL-128) | WB, Block, FuncS | Mouse IgG |
| MOB-0309MZ | Recombinant Mouse Anti-Human ERBB3 Antibody (clone EAK-H4-IC) | IHC | Mouse antibody |
| HPAB-0286-YC | Mouse Anti-ERBB3 Recombinant Antibody (clone 1153) | ELISA, FuncS, FC | Mouse IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0508CL | Anti-Human ERBB3 Recombinant Antibody (1A5) | ELISA, FC, Inhib, FuncS | |
| TAB-0509CL | Anti-Human ERBB3 Recombinant Antibody (3D4) | Inhib, FC | |
| TAB-0552CL | Mouse Anti-ERBB3 Recombinant Antibody (TAB-0552CL) | ELISA, Inhib | Mouse IgG |
| TAB-0553CL | Mouse Anti-ERBB3 Recombinant Antibody (TAB-0553CL) | ELISA, Inhib | Mouse IgG |
| TAB-0508CL-S(P) | Anti-Human ERBB3 Recombinant Antibody scFv Fragment (1A5) | ELISA, Inhib, FuncS |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-061CT | Human Anti-ERBB3 Recombinant Antibody (TAB-061CT) | Inhib, ELISA | Chimeric (Rabbit/Human) antibody |
| TAB-061CT-S(P) | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-061CT-S(P)) | Inhib, ELISA | Human scFv |
| TAB-061CT-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-061CT-F(E)) | Inhib, ELISA | Chimeric (Rabbit/Human) Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-738CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone CBL932) | Neut, IP | Mouse IgG1 |
| NEUT-739CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone CBL483) | FC, CyTOF®, ELISA, Neut | Mouse IgG1 |
| NEUT-740CQ | Human Anti-ERBB3 Recombinant Antibody (clone CBL1019) | Neut | Human IgG1, κ |
| NEUT-741CQ | Human Anti-ERBB3 Recombinant Antibody (clone CBL1020) | Neut | Human IgG1, κ |
| NEUT-742CQ | Mouse Anti-ERBB3 Recombinant Antibody (clone M908) | Neut | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1179 | Hi-Affi™ Rabbit Anti-ERBB3 Recombinant Antibody (clone DS1179AB) | ICC, IF, WB | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0286-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 1153); Fab Fragment | ELISA, FuncS, FC | Mouse Fab |
| HPAB-0287-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 920104); Fab Fragment | ELISA, FuncS, FC | Mouse Fab |
| HPAB-0288-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 1126); Fab Fragment | ELISA, FuncS, FC | Mouse Fab |
| HPAB-0289-YC-F(E) | Mouse Anti-ERBB3 Recombinant Antibody (clone 12511); Fab Fragment | ELISA, FuncS, FC | Mouse Fab |
| HPAB-0290-YC-F(E) | Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-0290-YC-F(E)) | ELISA, FuncS, FC | Human Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-H21 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Duligotumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
| AFC-TAB-422CQ | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Elgemtumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, BL | ADCC enhanced antibody |
| AFC-TAB-189 | Afuco™ Anti-ERBB3 Recombinant Antibody (AFC-TAB-189), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | Human IgG1, κ |
| AFC-TAB-H22 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Duligotuzumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| AFC-TAB-892 | Afuco™ Anti-ERBB3 ADCC Recombinant Antibody (Seribantumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0436-FY-S(P) | Mouse Anti-ERBB3 Recombinant Antibody (clone 15D5); scFv Fragment | Inhib | Mouse scFv |
| HPAB-0437-FY-S(P) | Mouse Anti-ERBB3 Recombinant Antibody (clone 1D9); scFv Fragment | Inhib | Humanized scFv |
| HPAB-0438-FY-S(P) | Mouse Anti-ERBB3 Recombinant Antibody (clone 993); scFv Fragment | FC, Inhib | Mouse scFv |
| FAMAB-0047JF-S(P) | Human Anti-ERBB3 Recombinant Antibody (clone PM6); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| PSBS-0069 | Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (PSBS-0069) | ELISA, Block, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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