Mouse Anti-PRNP Recombinant Antibody (clone POM1); Fab Fragment (CAT#: PABX-161-F(E))
This product is a recombinant mouse antibody Fab fragment that recognizes human PRNP.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/if_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/if_selected.jpg
Figure 2 IHC staining of human cerebellum
(Immunohistochemical staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/ihc_selected.jpg
(Immunohistochemical staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/ihc_selected.jpg
Figure 3 Cerebral cortex
(Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_B_7_5.jpg
(Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_B_7_5.jpg
Figure 4 Caudate
(Neuronal cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/95554_B_9_7.jpg
(Neuronal cells
Staining:
Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/95554_B_9_7.jpg
Figure 5 Colon
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_A_9_3.jpg
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_A_9_3.jpg
Figure 6 RNA cell line category: Cell line enhanced (WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171867-PRNP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171867-PRNP
Figure 6 RNA cell line category: Cell line enhanced (WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171867-PRNP
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171867-PRNP
Specifications
- Host Species
- Mouse
- Type
- Mouse Fab
- Specificity
- Human PRNP
- Species Reactivity
- Human
- Clone
- POM1
- Applications
- ELISA, IP, IHC, FuncS
- Related Disease
- Prion diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C; major prion protein; alternative prion protein; CD230 antigen; prion-related protein
- Gene ID
- 5621
- UniProt ID
- P04156
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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ScFv-Fc Chimera Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1227z | Mouse Anti-PRNP Recombinant Antibody (clone 25G7) | WB, IP, IF, IHC, FC, ELISA | Mouse IgG1, κ |
| PABW-089 | Mouse Anti-PRNP Recombinant Antibody (clone 3F4) | ELISA | Mouse IgG2a |
| FAMAB-0272CQ | Human Anti-PRNP Recombinant Antibody (clone ch31C6) | ELISA, WB, IHC | Chimeric (mouse/human) IgG1 |
| FAMAB-0273CQ | Mouse Anti-PRNP Recombinant Antibody (clone mAb 106) | ELISA, WB, IHC | Mouse IgG2b, κ |
| FAMAB-0274CQ | Mouse Anti-PRNP Recombinant Antibody (clone mAb 110) | ELISA, WB, IHC | Mouse IgG2a, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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