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AFP

Anti-AFP ProductsBackground
Anti-AFP Products
- Human Anti-AFP Recombinant Soluble TCR (clone TG1) (scTCR-0062YC-S(P))
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- Species Reactivity: Human
- Epitope: FMNKFIYEI
- MHC: HLA-A2
- Human Anti-AFP Recombinant Soluble TCR (clone VC3) (scTCR-0063YC-S(P))
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- Species Reactivity: Human
- Epitope: GLSPNLNRFL
- MHC: HLA-A2
- Recombinant Human Anti-AFP Soluble TCR (TG1) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1363)
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- Species Reactivity: Human
- Epitope: FMNKFIYEI
- MHC: HLA-A2
- Recombinant Human Anti-AFP Soluble TCR (VC3) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1364)
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- Species Reactivity: Human
- Epitope: GLSPNLNRFL
- MHC: HLA-A2
- Recombinant Human Anti-AFP Soluble TCR (TG1) (C-Cys) (VS-0622-YF4071)
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- Species Reactivity: Human
- Epitope: FMNKFIYEI
- MHC: HLA-A2
- Recombinant Human Anti-AFP Soluble TCR (VC3) (C-Cys) (VS-0622-YF4072)
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- Species Reactivity: Human
- Epitope: GLSPNLNRFL
- MHC: HLA-A2
- Recombinant Human Anti-AFP Soluble TCR (TG1) (KIH) (VS-0622-YF6779)
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- Species Reactivity: Human
- Epitope: FMNKFIYEI
- MHC: HLA-A2
- Recombinant Human Anti-AFP Soluble TCR (VC3) (KIH) (VS-0622-YF6780)
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- Species Reactivity: Human
- Epitope: GLSPNLNRFL
- MHC: HLA-A2
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
