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CD33 & FcγRIII
Loading...Anti-CD33 & FcγRIII Products
- Anti-CD33 Recombinant Antibody (TAB-756) (TAB-756)
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
- Mouse Anti-CD33 Recombinant Antibody (TAB-119LC) (TAB-119LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, IF, RIA
- Mouse Anti-CD33 Recombinant Antibody (TAB-122LC) (TAB-122LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Cyt
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: ELISA, FC, IF, IHC, IP, FuncS
- Mouse Anti-CD33 Recombinant Antibody (TAB-130LC) (TAB-130LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Human Anti-CD33 Recombinant Antibody (TAB-146LC) (TAB-146LC)
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- Species Reactivity: Human, Monkey
- Type: Human IgG
- Application: ELISA
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- Class: Class I
- Antigen: CD33 A65Y
- Antigen Species: Human
- Peptide: YIISGDSPV
- Conjugate: PE
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- Class: Class I
- Antigen: CD33 A65Y
- Antigen Species: Human
- Peptide: YIISGDSPV
- Conjugate: APC
- Anti-Human CD33 Recombinant Antibody (TAB-471CQ) (TAB-471CQ)
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: IgG1, κ
- Application: ELISA, IHC, FC, IP, IF, FuncS
- Human Anti-CD33 Recombinant Antibody (HPAB-M0471-YC) (HPAB-M0471-YC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FuncS
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- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: ELISA, IHC, FC, IP, IF, FuncS
- Mouse Anti-CD33 Recombinant Antibody (HPAB-676-FY) (HPAB-676-FY)
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse IgG
- Application: FC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG4, κ
- Application: IF, IP, Neut, FuncS, ELISA, FC, WB
- Anti-Human CD33 Recombinant Antibody (TAB-123LC)
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- Type: Human antibody
- Application: FC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, FC, IP, FuncS, IF, Neut, IHC
- Anti-Human CD33 Recombinant Antibody scFv Fragment (TAB-123LC-S(P))
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- Type: Human antibody
- Application: FC
- Anti-Human CD33 Recombinant Antibody Fab Fragment (TAB-123LC-F(E))
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- Type: Human antibody
- Application: FC
- APC-A*02:01/Human CD33 (AIISGDSPV) MHC Tetramer (MHC-LC162)
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- Class: Class I
- Antigen: CD33
- Antigen Species: Human
- Peptide: AIISGDSPV
- Conjugate: APC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: IF, IP, Neut, FuncS, ELISA, FC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Application: IF, IP, Neut, FuncS, ELISA, FC
- Human Anti-CD33 Recombinant Antibody (HPAB-1910LY) (HPAB-1910LY)
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized IgG
- Application: FC, Inhib, FuncS
- Human Anti-CD33 Recombinant Antibody (HPAB-1911LY) (HPAB-1911LY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC, SPR, FuncS
- Human Anti-CD33 Recombinant Antibody (HPAB-1912LY) (HPAB-1912LY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
- Human Anti-CD33 Recombinant Antibody (HPAB-1913LY) (HPAB-1913LY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC, SPR
- Human Anti-CD33 Recombinant Antibody (HPAB-1914LY) (HPAB-1914LY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
- Human Anti-CD33 Recombinant Antibody (HPAB-1915LY) (HPAB-1915LY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: FC
- PE-A*02:01/Human CD33 (AIISGDSPV) MHC Tetramer (MHC-LC2064)
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- Class: Class I
- Antigen: CD33
- Antigen Species: Human
- Peptide: AIISGDSPV
- Conjugate: PE
- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-0077-LSX-S(P)) (HPAB-0077-LSX-S(P))
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- Species Reactivity: Human, Mammal
- Type: Mouse scFv
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-0078-LSX-S(P)) (HPAB-0078-LSX-S(P))
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- Species Reactivity: Human, Mammal
- Type: Mouse scFv
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-0079-LSX-S(P)) (HPAB-0079-LSX-S(P))
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- Species Reactivity: Human, Mammal
- Type: Mouse scFv
- Application: ELISA, FC
- Human Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-0080-LSX-S(P)) (HPAB-0080-LSX-S(P))
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- Derivation: Human
- Species Reactivity: Human, Cynomolgus monkey
- Type: Human scFv
- Application: ELISA
- Human Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-0081-LSX-S(P)) (HPAB-0081-LSX-S(P))
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- Derivation: Human
- Species Reactivity: Human, Cynomolgus monkey
- Type: Human scFv
- Application: ELISA
- Recombinant Anti-human CD33 VHH Single Domain Antibody (NAB-321-sdAb)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, IP, ChiP, Neut, ELISA
- Human Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-0082-LSX-S(P)) (HPAB-0082-LSX-S(P))
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- Derivation: Human
- Species Reactivity: Human, Cynomolgus monkey
- Type: Human scFv
- Application: ELISA
- Human Anti-CD33 Recombinant Antibody; scFv Fragment (HPAB-0083-LSX-S(P)) (HPAB-0083-LSX-S(P))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Human scFv
- Application: ELISA
- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-124LC-F(E)) (TAB-124LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-125LC-F(E)) (TAB-125LC-F(E))
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse Fab
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-119LC-S(P)) (TAB-119LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, IF, RIA
- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-120LC-S(P)) (TAB-120LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-121LC-S(P)) (TAB-121LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-122LC-S(P)) (TAB-122LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-124LC-S(P)) (TAB-124LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-125LC-S(P)) (TAB-125LC-S(P))
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse scFv
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-126LC-S(P)) (TAB-126LC-S(P))
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse scFv
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-127LC-S(P)) (TAB-127LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody; scFv Fragment (TAB-128LC-S(P)) (TAB-128LC-S(P))
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse scFv
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-119LC-F(E)) (TAB-119LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, IF, RIA
- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-120LC-F(E)) (TAB-120LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-121LC-F(E)) (TAB-121LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-CD33 Recombinant Antibody; Fab Fragment (TAB-122LC-F(E)) (TAB-122LC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA
- Mouse Anti-CD33 Recombinant Antibody (TAB-124LC) (TAB-124LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-120LC) (TAB-120LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Cyt
- Mouse Anti-CD33 Recombinant Antibody (TAB-121LC) (TAB-121LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- anti-CD33 immunotoxin M195 (IgG)-PE (AGTO-L050E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
- Anti-CD33 immunotoxin (scFv)-PE (AGTO-G008E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
- Mouse Anti-CD33 Recombinant Antibody (TAB-135LC) (TAB-135LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-136LC) (TAB-136LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC, FuncS
- Mouse Anti-CD33 Recombinant Antibody (TAB-137LC) (TAB-137LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-138LC) (TAB-138LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-139LC) (TAB-139LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-140LC) (TAB-140LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-141LC) (TAB-141LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-142LC) (TAB-142LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-143LC) (TAB-143LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-144LC) (TAB-144LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Human Anti-CD33 Recombinant Antibody (TAB-145LC) (TAB-145LC)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, FC
- Anti-CD33 immunotoxin (scFv)-Gel (AGTO-G008G)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
- Mouse Anti-CD33 Recombinant Antibody (TAB-125LC) (TAB-125LC)
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-126LC) (TAB-126LC)
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-127LC) (TAB-127LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-128LC) (TAB-128LC)
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-129LC) (TAB-129LC)
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, FC
- Human Anti-CD33 Recombinant Antibody; Fab Fragment (HPAB-1910LY-F(E)) (HPAB-1910LY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human, Mouse
- Type: Humanized Fab
- Application: FC
- Human Anti-CD33 Recombinant Antibody; Fab Fragment (HPAB-1911LY-F(E)) (HPAB-1911LY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
- Human Anti-CD33 Recombinant Antibody; Fab Fragment (HPAB-1912LY-F(E)) (HPAB-1912LY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
- Human Anti-CD33 Recombinant Antibody; Fab Fragment (HPAB-1913LY-F(E)) (HPAB-1913LY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: FC
- Human Anti-CD33 Recombinant Antibody (clone huM195); Fab Fragment (FAMAB-0045CQ-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: ELISA, FC
- Human Anti-CD33 Recombinant Antibody Fab Fragment (HPAB-0307-FY-F(E)) (HPAB-0307-FY-F(E))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: WB
- Mouse Anti-CD33 Recombinant Antibody (TAB-133LC) (TAB-133LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-134LC) (TAB-134LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-147LC) (TAB-147LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-131LC) (TAB-131LC)
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD33 Recombinant Antibody (TAB-132LC) (TAB-132LC)
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- Species Reactivity: Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA, FC, FuncS
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Classification: Fab glycosylation
- Glycosylation site: Asn73 in FR of VH
- Anti-CD33 (clone h2H12)-mc-MMAF ADC (ADC-146CL)
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- Target: CD33
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC, IP
- Anti-CD33mAb-DOTA-SH ADC (ADC-059LCT)
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- Target: CD33
- Linker: DOTA-SH
- Anti-CD33 (clone hP67.6)-calicheamicin ADC (ADC-143CL)
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- Target: CD33
- Drug: calicheamicin
- Anti-CD33 (Gemtuzumab)-hydrazone-Calicheamicin ADC (ADC-060LCT)
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- Target: CD33
- Linker: hydrazone
- Drug: Calicheamicin
- Anti-CD33 (clone h2H12d) ADC (ADC-144CL)
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- Target: CD33
- Anti-CD33 (HuM195)-SPDB-DM4 ADC (ADC-061LCT)
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- Target: CD33
- Linker: SPDB
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
- Anti-CD33 (clone m2H12)-mc-MMAF ADC (ADC-145CL)
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- Target: CD33
- Linker: Mc (maleimidocaproyl)
- Drug: MMAF (Monomethyl auristatin F)
- Anti-CD33 (clone h2H12) ADC (ADC-093CL)
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- Target: CD33
- Anti-CD33 (HuM195)-AcBut-Calicheamicin ADC (ADC-056LCT)
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- Target: CD33
- Linker: AcBut
- Drug: Calicheamicin
- Anti-CD33mAb-DOTA-G3FC ADC (ADC-057LCT)
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- Target: CD33
- Linker: DOTA-G3FC
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- Targets: CD33 & FcγRIII
- Type: Tandem Diabody
- Application: FuncS, Promising therapeutic agent
- Anti-CD33 (clone hP67.6)-AcBut-Calicheamicin ADC (ADC-007LZY)
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- Target: CD33
- Linker: AcBut (4-(4-acetylphenoxy)butanoic acid)
- Drug: Calicheamicin
- Anti-CD33 (clone huMy9-6)-SPDB-DM4 ADC (ADC-023LZY)
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- Target: CD33
- Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
- Anti-CD33 (clone h2H12ec)-mc-vc-PBD ADC (ADC-044LZY)
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- Target: CD33
- Linker: mc-VC (maleimidocaproyl-valine-alanine)
- Drug: pyrrolobenzodiazepine (PBD) dimers
- Anti-CD33mAb-DOTA-NCS ADC (ADC-058LCT)
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- Target: CD33
- Linker: DOTA-NCS
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For Research Use Only. Not For Clinical Use.
Background
CD33 (CD33 Molecule) is a Protein Coding gene. Diseases associated with CD33 include Gallbladder Lymphoma and Extracutaneous Mastocytoma. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Immune System. Gene Ontology (GO) annotations related to this gene include receptor activity and carbohydrate binding. An important paralog of this gene is SIGLEC6.
This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.


