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CD82

Anti-CD82 Products

Hi-Affi™ Rabbit Anti-CD82 Recombinant Antibody (clone DS585AB) (MOR-0585)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: FC, IHC-P, WB
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For Research Use Only. Not For Clinical Use.

Background

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the tetraspanin/transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients.