CXCR4

Anti-CXCR4 Recombinant Antibody Products

AbPlus™ Anti-CXCR4 Magnetic Beads (VS-0724-YC1489) (VS-0724-YC1489)
- Target: CXCR4
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome.