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DCSTAMP
Loading...Anti-DCSTAMP Products
- Recombinant Anti-human DC-STAMP VHH Single Domain Antibody (NAB-433-sdAb)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: IHC, IP, FC, Neut, FUNC
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- Anti-Human DCSTAMP Recombinant Antibody (TAB-210CL)
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- Species Reactivity: Human
- Type: Antibody
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a seven-pass transmembrane protein that is primarily expressed in dendritic cells. The encoded protein is involved in a range of immunological functions carried out by dendritic cells. This protein plays a role in osteoclastogenesis and myeloid differentiation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
Protein class
Transporters
Predicted location
Membrane
Single cell type specificity
Group enriched (Hofbauer cells, Macrophages)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (U-87 MG)
Interaction
Monomer. Homodimer. Isoform 1 interacts (via the C-terminus cytoplasmic tail) with OS9 isoform 1 (via the C-terminus tail); the interaction induces DCSTAMP redistribution to the endoplasmic reticulum-Golgi intermediate compartment. Isoform 1 interacts (via the C-terminus cytoplasmic tail) with OS9 isoform 2 (via the C-terminus tail) (By similarity). Interacts with CREB3.
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