Drosophila FMR1

Enables several functions, including DEAD/H-box RNA helicase binding activity; N6-methyladenosine-containing RNA binding activity; and protein self-association. Involved in several processes, including gamete generation; generation of neurons; and learning or memory. Located in Golgi membrane; cytoplasmic ribonucleoprotein granule; and neuronal cell body. Part of RISC complex and messenger ribonucleoprotein complex. Is expressed in several structures, including gastrula embryo; gonad; gut section; muscle system; and nervous system. Used to study autism spectrum disorder; fragile X syndrome; and malignant pleural mesothelioma. Human ortholog(s) of this gene implicated in fragile X syndrome; fragile X-associated tremor/ataxia syndrome; and primary ovarian insufficiency 1.