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ICOSLG

Anti-ICOSLG ProductsBackground
Anti-ICOSLG Products
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- Derivation: Human
- Species Reactivity: Human
- Type: Human IgG2, κ
- Application: ELISA, IHC, FC, IP, IF, Inhib
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC
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For Research Use Only. Not For Clinical Use.
Background
ICOSLG (Inducible T Cell Costimulator Ligand) is a Protein Coding gene. Diseases associated with ICOSLG include Inclusion Body Myositis and Immunodeficiency With Hyper-Igm, Type 2. Among its related pathways are Allograft rejection and Innate Immune System. Gene Ontology (GO) annotations related to this gene include receptor binding. An important paralog of this gene is LOC102723996.

Protein class
CD markers, Plasma proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Langerhans cells, B-cells, Glandular and luminal cells, monocytes)
Immune cell specificity
Immune cell enhanced (naive B-cell)
Cell line specificity
Cell line enhanced (Daudi)
Interaction
Interacts with CTLA4 (in vitro).
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