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Target
Application
Host
Type
Species Reactivity
Expression Host
Conjugate
MUTYH
Loading...Anti-MUTYH ProductsBackground
Anti-MUTYH Products
- Recombinant Mouse Anti-Human MUTYH Antibody (MOB-1031MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Protein class
Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Cytotrophoblasts)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Molecular function
Glycosidase, Hydrolase
More Types Infomation