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Anti-Ricin Products

Recombinant Mouse Anti-Ricin Antibody Fab Fragment (RAC18) (PABX-165-F (E))
- Derivation: Mouse
- Species Reactivity: Ricinus communis
- Type: Fab
- Application: Neut, FuncS
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Recombinant Mouse Anti-Ricin Antibody scFv Fragment (RAC18) (PABX-165-S (P))
- Derivation: Mouse
- Species Reactivity: Ricinus communis
- Type: scFv
- Application: Neut, FuncS
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Recombinant Mouse Anti-Ricin Antibody (RAC18) (PABX-165)
- Derivation: Mouse
- Species Reactivity: Ricinus communis
- Type: IgG
- Application: FuncS, IF
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Recombinant Anti-Castor Bean RTA VHH Single Domain Antibody (PNBL-063) (PNBL-063)
- Derivation: Llama
- Species Reactivity: Castor Bean
- Type: Llama VHH
- Application: ELISA, Neut
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Recombinant Anti-Castor Bean RTA VHH Single Domain Antibody (PNBL-062) (PNBL-062)
- Derivation: Llama
- Species Reactivity: Castor Bean
- Type: Llama VHH
- Application: ELISA, Neut
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Recombinant Anti-Castor Bean RTA VHH Single Domain Antibody (PNBL-060) (PNBL-060)
- Derivation: Llama
- Species Reactivity: Castor Bean
- Type: Llama VHH
- Application: ELISA, Neut
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Recombinant Anti-Castor Bean RTA VHH Single Domain Antibody (PNBL-057) (PNBL-057)
- Derivation: Llama
- Species Reactivity: Castor Bean
- Type: Llama VHH
- Application: ELISA, Neut
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Recombinant Anti-Castor Bean RTA VHH Single Domain Antibody (PNBL-041) (PNBL-041)
- Derivation: Llama
- Species Reactivity: Castor Bean
- Type: Llama VHH
- Application: ELISA, Neut
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For Research Use Only. Not For Clinical Use.

Background

Ricin is a 60-65 kDa glycoprotein derived from castor beans [1]. It consists of a ricin toxin enzymatic-A (RTA) and a ricin toxin lectin-B (RTB) linked by a disulfide bond. RTB binding to galactose residues on cells triggers cellular uptake of the ricin [2] and facilitates transport of the RTA from endoplasmic reticulum to the cytosol [3], [4].

This gene encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. Multiple transcript variants encoding different isoforms have been found for this gene.