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TACR1

Anti-TACR1 ProductsBackground
Anti-TACR1 Products
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: IP, WB
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For Research Use Only. Not For Clinical Use.
Background
Enables substance P receptor activity. Involved in several processes, including learning or memory; positive regulation of cell communication; and regulation of cell migration. Located in cell body; cell surface; and dendrite. Is active in postsynaptic membrane. Used to study central sleep apnea; cystitis; pancreatitis; and pulmonary hypertension. Biomarker of acute necrotizing pancreatitis; allergic rhinitis; asthma; colitis; and respiratory syncytial virus infectious disease. Human ortholog(s) of this gene implicated in developmental disorder of mental health and exercise-induced bronchoconstriction. Orthologous to human TACR1 (tachykinin receptor 1).
Protein class
FDA approved drug targets, G-protein coupled receptors
Predicted location
Membrane
Single cell type specificity
Cell type enriched (Inhibitory neurons)
Immune cell specificity
Immune cell enriched (basophil)
Cell line specificity
Not detected
Interaction
Interacts with ARRB1.
Molecular function
G-protein coupled receptor, Receptor, Transducer
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