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TNNI3
Loading...Anti-TNNI3 ProductsBackground
Anti-TNNI3 Products
- Mouse Anti-TNNI3 Recombinant Antibody (NEUT-2209CQ) (NEUT-2209CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA, Inhib, WB
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- Mouse Anti-TNNI3 Recombinant Antibody (VMC208) (NEUT-2210CQ)
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- Species Reactivity: Bovine, Canine, Feline, Fish, Goat, Human, Mouse, Porcine, Rabbit, Rat
- Type: Mouse IgG2b
- Application: ELISA, Inhib, WB
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- Mouse Anti-TNNI3 Recombinant Antibody (clone 4C2) (NEUT-2211CQ)
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- Species Reactivity: Bovine, Canine, Feline, Goat, Human, Mouse, Porcine, Rabbit, Rat
- Type: Mouse IgG2a
- Application: ELISA, Inhib, WB
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For Research Use Only. Not For Clinical Use.
Background
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).