A*0201/HTLV-1 Tax (LLFGYPVYV) MHC Tetramer
CAT#: MHC-LC757
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of HTLV-1-derived peptide of LLFGYPVYV sequence covering 11-19 and A*0201 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- A*0201
- Class
- Class I
- MHC Species
- Human
- Antigen
- HTLV-1 Tax
- Antigen Species
- HTLV-1
- Peptide
- LLFGYPVYV
- Range
- 11-19
- Application
- FCM
Target
- Antigen Introduction
- Human T-cell lymphotropic virus type 1 or human T-lymphotropic virus type 1 (HTLV-I), also called the adult T-cell lymphoma virus type 1, is a retrovirus of the human T-lymphotropic virus (HTLV) family that has been implicated in several kinds of diseases including very aggressive adult T-cell lymphoma (ATL), HTLV-I-associated myelopathy, uveitis, Strongyloides stercoralis hyper-infection and some other diseases. However, only about 1–5% of infected persons are thought to develop cancer as a result of the infection with HTLV-I over their lifetimes.
- Alternative Names
- HTLV-1 tax; Human T-cell lymphotropic virus type 1 tax; HTLV-1 p40
- Gene ID
- 1491938
- UniProt ID
- P14079
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