APC-A*24:02/Human MAGEA2 (EYLQLVFGI) MHC Tetramer
CAT#: MHC-LC124
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of MAGE-A2-derived peptide of EYLQLVFGI sequence covering 156-164 and A*24:02 molecule. The pMHC tetramer recognizes human CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (GAMG, HMC-1, K-562, OE19, SH-SY5Y, SK-BR-3, U-266/70, U-266/84)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000268606-MAGEA2
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Specifications
- Allele
- A*24:02
- Class
- Class I
- MHC Species
- Human
- Antigen
- MAGE-A2
- Antigen Species
- Human
- Peptide
- EYLQLVFGI
- Range
- 156-164
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
- Alternative Names
- MAGEA2; MAGE family member A2; CT1.2; MAGE2; MAGEA2A
- Gene ID
- 4101
- UniProt ID
- P43356
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