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APC-B44/Human RASA2 (AEIPRTFKY) MHC Tetramer (CAT#: MHC-LC3444)

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human RASA2 of peptide AEIPRTFKY and B44 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.


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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line A-431
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35374/if_selected.jpg
Normal Tissue
Figure 2 IHC staining of human cerebellum
Figure 2 IHC staining of human cerebellum
(Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35375/ihc_selected.jpg
Figure 3 Liver
Figure 3 Liver
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35374/70093_A_7_4.jpg
Figure 4 Testis
Figure 4 Testis
(Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Sertoli cells Staining: Medium Intensity: Strong Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35374/70093_A_4_6.jpg
RNA Expression
Figure 5 RNA cell line category: Low cell line specificity
Figure 5 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000155903-RASA2

Specifications

  • Allele
  • B44
  • Class
  • Class I
  • MHC Species
  • Human
  • Antigen
  • RASA2
  • Antigen Species
  • Human
  • Peptide
  • AEIPRTFKY
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants.
  • Alternative Names
  • RASA2; RAS p21 protein activator 2; GAP1M

Downloads

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See other products for "RASA2"

Recombinant Antibody

CAT Product Name Application Type
MOB-2631z Mouse Anti-RASA2 Recombinant Antibody (clone 12G6) WB, IF Mouse IgG1

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC3439 PE-B44/Human RASA2 (AEIPRTFKY) MHC Tetramer FCM

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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