APC-DQ8/T. aestivum Prolamin MM1 (QQYPSGEGSFQPSQENPQ) MHC Tetramer
CAT#: MHC-LC1374
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of T. aestivum Prolamin MM1-derived peptide of QQYPSGEGSFQPSQENPQ covering 242-259 and DQ8 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- DQ8
- Class
- Class II
- MHC Species
- Human
- Antigen
- T. aestivum Prolamin MM1
- Antigen Species
- Triticum aestivum
- Peptide
- QQYPSGEGSFQPSQENPQ
- Range
- 242-259
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- Common wheat (Triticum aestivum), also known as bread wheat, is a cultivated wheat species. About 95% of the wheat produced is common wheat, which is the most widely grown of all crops, and the cereal with the highest monetary yield.
- Alternative Names
- T. aestivum Prolamin MM1; Triticum aestivum Alpha/beta-gliadin MM1
- UniProt ID
- P18573
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Perfect for Multicolor Flow Cytometry
With its compatibility with other markers, the tetramer enhances experiments aimed at a broad-based immune cell profiling. It offers detailed information necessary for comprehensive studies of T cell responses in autoimmune conditions.
Reliable and Reproducible Results
The tetramer's consistency across multiple experiments ensures reliable data generation, which is vital for longitudinal studies examining T cells' role in autoimmune pathology, particularly regarding celiac disease.
Q&As
-
What storage conditions are recommended to maintain the functionality of this MHC tetramer?
A: Store the tetramer at 4°C and avoid freeze-thaw cycles to maintain its performance. For consistent results, consider aliquoting for long-term storage to pQAent degradation.
-
Can this MHC tetramer be used with other markers for broader immune profiling?
A: Yes, it can be used with various fluorescently labeled antibodies, enhancing its use in multicolor flow cytometry for comprehensive T cell characterization, including phenotype and activation state analyses.
View the frequently asked questions answered by Creative Biolabs Support.
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