Anti-Human APP Recombinant Antibody (3D6) (CAT#: TAB-0809CLV)
The anti-β-amyloid antibody 3D6 refers to a recombinant antibody expressed on the macrophage, the specific antibody can be used in the treatment of Alzheimer's Disease.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
IF
Figure 1 Robust increases of extracellular amyloid-b deposits in 3D-differentiated hNPCs with FAD mutations.
Amyloid-β deposits in 6-week differentiated control and FAD ReN cells in 3D Matrigel (green, GFP; blue, 3D6; scale bar, 25 mm; arrowheads, extracellular amyloid-b deposits; right-most panels, 3D6 staining was pseudo-coloured to red).
Choi, S. H., Kim, Y. H., Hebisch, M., Sliwinski, C., Lee, S., D’Avanzo, C., ... & Klee, J. B. (2014). A three-dimensional human neural cell culture model of Alzheimer’s disease. Nature, 515(7526), 274.
Specifications
- Host Species
- Mouse
- Specificity
- Human
- Clone
- 3D6
- Applications
- IF
- Related Disease
- Alzheimer's disease
Applications
- Application Notes
- The antibody was validated for Immunofluorescence. For details, refer to Published Data.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1185z | Mouse Anti-APP Recombinant Antibody (clone 25F3) | WB, FC, ICC, IF, IHC | Mouse IgG1 |
| PABW-009 | Mouse Anti-APP Recombinant Antibody (clone PFA1) | ELISA | Mouse IgG2a |
| PABC-010 | Mouse Anti-APP Recombinant Antibody (clone PFA2) | ELISA | Mouse IgG2a |
| HPAB-0176-FY | Mouse Anti-APP Recombinant Antibody (HPAB-0176-FY) | AG | Mouse IgG1, κ |
| ZG-0195U | Mouse Anti-APP Recombinant Antibody (clone 5A11E5) | ELISA, WB, IHC, IF | Mouse IgG |
Customer Reviews and Q&As
Customer Review
Q&As
Simple to operate
It is simple to handle and prepare the antibody. There were comprehensive usage instructions included with the product, so no more adjustments were required.
Consistent Storage
This antibody has not degraded after being stored for more than six months at -20°C. It keeps its reactivity well and is incredibly stable.
Minimal Background
The antibody shows minimal nonspecific binding even in the absence of 100% blocking, which makes it a dependable choice for our immunofluorescence research.
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-0809CLV, RRID: AB_3111798)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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