1 0
Cart
    Inquiry
    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein

    Afuco™ Anti-Human CD19 ADCC Recombinant Antibody (MDX-1342), ADCC Enhanced (CAT#: AFC-104CL)

    Anti-CD19 ADCC Enhanced Antibody (MDX-1342) is an ADCC enhanced antibody produced by our Afuco™ platform. MDX-1342 is a fully human monoclonal antibody (HuMAb) with enhanced antibody-dependent cellular cytotoxicity (ADCC) effector function, targeting CD19-membrane receptor which is highly expressed on malignant chronic lymphocytic leukemia (CLL) cells.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Colon
    Figure 1 Colon
    (Mucosal lymphoid cells
    Staining:Medium
    Intensity: Strong
    Quantity: <25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_7_3.jpg
    Figure 2 Testis
    Figure 2 Testis
    (Leydig cells
    Staining:Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_5_6.jpg
    Figure 3 Appendix
    Figure 3 Appendix
    (Germinal center cells
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%
    Non-germinal center cells
    Staining:High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_2_2.jpg
    Figure 4 Lymph node
    Figure 4 Lymph node
    (Germinal center cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/16110/36120_A_9_8.jpg
    RNA Expression
    Figure 5 RNA cell line category: Cell line enhanced (Daudi, REH, U-698)
    Figure 5 RNA cell line category: Cell line enhanced (Daudi, REH, U-698)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000177455-CD19

    Specifications

    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • ADCC enhanced antibody
    • Species Reactivity
    • Human
    • Related Disease
    • Chronic Lymphocytic Leukemia; Rheumatoid Arthritis

    Product Property

    • Purity
    • >90% assessed by SDS-PAGE
    • Storage
    • Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.

    Target

    • Alternative Names
    • CD19; CD19 molecule; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4

    Related Resources

    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "CD19"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    IgG Antibodies Humanized Antibodies Immunotoxins Chimeric Antibodies Human Antibodies Mouse Antibodies Fc Glycosylation Antibodies Low- or Non-fucosylated Oligosaccharide Antibodies Chicken IgY Antibodies Neutralizing Antibodies Blocking Antibodies Rabbit Monoclonal Antibodies ScFv Antibodies Fab Antibodies ADCC Enhanced Antibodies Antibody Magnetic Beads NHP Antibodies FC Reagents & Kits ScFv-Fc Chimeras Extracellular Vesicle Antibodies IHC Kits & Antibodies
    CAT Product Name Application Type
    MOB-1087z Mouse Anti-CD19 Recombinant Antibody (clone 32B9) WB, FC, ICC, IF, FuncS Mouse IgG1
    HPAB-0264-CN Human Anti-CD19 Recombinant Antibody (HPAB-0264-CN) ELISA, FC Humanized IgG1, κ
    HPAB-0265-CN Human Anti-CD19 Recombinant Antibody (HPAB-0265-CN) ELISA, FC Humanized IgG1, κ
    HPAB-0266-CN Human Anti-CD19 Recombinant Antibody (HPAB-0266-CN) ELISA, FC Humanized IgG
    HPAB-0267-CN Human Anti-CD19 Recombinant Antibody (HPAB-0267-CN) ELISA, FC Humanized IgG

    Customer Reviews and Q&As

    Customer Review Q&As

    Submit a review or a question


    Superior ADCC Activity
    The ADCC enhancement in this antibody is remarkable. It has significantly improved the effectiveness of our in vitro cytotoxicity assays against CD19+ B cells.

    High Specificity
    The specificity of this antibody for CD19 is impressive. It has minimal off-target effects, which is crucial for our studies of B cell signaling pathways.

    Popular products with customers

    Figure 4 Anti-Human PCSK9 Recombinant Antibody (TAB-H31) in HPLC

    Human Anti-PCSK9 Recombinant Antibody (TAB-H31) (CAT# TAB-H31)
    Application: FC, IP, ELISA, Neut, FuncS, IF, IHC

    Figure 3 Anti-Human IL17RA Antibody (TAB-134) in DB

    Human Anti-IL17RA Recombinant Antibody (TAB-134) (CAT# TAB-134)
    Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

    Figure 2 Anti-S. Aureus Recombinant Antibody (TAB-029) in HPLC

    Anti-S. Aureus Recombinant Antibody (TAB-029) (CAT# TAB-029)
    Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

    Figure 2 Anti-Human CXCR4 Recombinant Antibody (TAB-H72) in HPLC

    Human Anti-Human CXCR4 Recombinant Antibody (TAB-H72) (CAT# TAB-H72)
    Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

    Figure 2 Anti-Human VEGF therapeutic Antibody Fab Fragment (TAB-012-F(E)) in Dot Blot

    Anti-Human VEGF Recombinant Antibody Fab Fragment (TAB-012-F(E)) (CAT# TAB-012-F(E))
    Application: IP, IF, FuncS, FC, Neut, ELISA, IHC

    Figure 3 Anti-Human IL17A Recombinant Antibody (TAB-H08) in DB

    Anti-Human IL17A/IL17F Recombinant Antibody (TAB-H08) (CAT# TAB-H08)
    Application: ELISA, FC, IP, FuncS, IF, Neut, WB

    Figure 2 Anti-Human CD24 Antibody (TAB-113CL) in WB

    Anti-Human CD24 Recombinant Antibody (CAT# TAB-113CL)
    Application:

    Figure 2 Anti-Human CD83 Recombinant Antibody (TAB-143CL) in HPLC

    Anti-Human CD83 Recombinant Antibody (CAT# TAB-143CL)
    Application:

    Figure 2 Human Anti-VEGF Recombinant Antibody (PABC-131) in ELISA

    Human Anti-VEGF Recombinant Antibody (clone B20-4) (CAT# PABC-131)
    Application: ELISA, Neut, Block

    Figure 2 Anti-Kallikrein-2 Recombinant Antibody (TAB-0622CL) in HPLC

    Mouse Anti-KLK2 Recombinant Antibody (TAB-0622CL) (CAT# TAB-0622CL)
    Application: FuncS, IF

    Figure 2 Anti-Mouse TIGIT Recombinant Antibody (TAB-0279CL) in HPLC

    Hamster Anti-TIGIT Recombinant Antibody (TAB-0279CL) (CAT# TAB-0279CL)
    Application: FuncS

    Figure 5 Recombinant Mouse Anti-Integrin alpha 1 Antibody (PABX-121) in ELISA

    Recombinant Mouse Anti-Integrin alpha 1 Antibody (AQC2) (CAT# PABX-121)
    Application: WB, ELISA, Neut, FuncS

    Figure 1 Human Anti-ROR1 Recombinant Antibody (HPAB-0181-LSX) in SDS-PAGE

    Human Anti-ROR1 Recombinant Antibody (HPAB-0181-LSX) (CAT# HPAB-0181-LSX)
    Application: ELISA, FC, IF, IHC, WB

    Figure 2 Human IgG1, lambda Isotype Control Antibody (MOB-173CQ) in HPLC

    Human IgG1, lambda Isotype Control Antibody (CAT# MOB-173CQ)
    Application: ELISA

    Figure 4 Mouse Anti-C5 Recombinant Antibody Fab Fragment (HPAB-0128CQ-F(E)) in ELISA

    Mouse Anti-C5 Recombinant Antibody (clone BB5.1); Fab Fragment (CAT# HPAB-0128CQ-F(E))
    Application: FC, FuncS, IA, IF, IP, IHC

    Figure 14 Human Anti-IAV HA Antibody (PABC-393) in DB 4

    Recombinant Human Anti-IAV HA Antibody (PABC-393) (CAT# PABC-393)
    Application: Neut, FuncS, ELISA

    Figure 3 Human Anti-IL18 Recombinant Antibody (clone h18-108); scFv Fragment (FAMAB-0041JF-S(P)) in ELISA

    Human Anti-IL18 Recombinant Antibody (clone h18-108); scFv Fragment (CAT# FAMAB-0041JF-S(P))
    Application: IB, FC, ELISA, FuncS

    Figure 3 Human Anti-IL21R Recombinant Antibody (FAMAB-1203CQ) in DB

    Human Anti-IL21R Recombinant Antibody (clone ATR-107) (CAT# FAMAB-1203CQ)
    Application: Inhib, FC, WB

    Figure 5 Mouse Anti-SERPINA1 Recombinant Antibody (PABJ-0203) in ELISA

    Mouse Anti-SERPINA1 Recombinant Antibody (clone 2H2) (CAT# PABJ-0203)
    Application: IF, FuncS

    Figure 1. Recombinant Rabbit Anti-VPS4A Antibody (clone R01-9H9) in WB.

    Recombinant Rabbit Anti-VPS4A Antibody (clone R01-9H9) (CAT# VS3-FY1548)
    Application: WB, IHC-Fr, IHC-P, ICC, IF

    For Research Use Only. Not For Clinical Use.

    Send Inquiry

    This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

    Go to compare

    Go to compare