Anti-Human IGF-1R Recombinant Antibody (1A) (CAT#: TAB-058ZJ)
Recombinant monoclonal antibody to insulin-like growth factor 1 receptor. A6 is a human antibody that can be potentially used in the treatment of tumor and cancer.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
FC
Figure 1 IGF-1R expression was up-regulated in SKOV3-T while HER2 was opposite by flow cytometry analysis.
IGF-1R can promote the proliferation of SKOV3.
Wang, W., Zhang, Y., Lv, M., Feng, J., Peng, H., Geng, J., ... & Ma, Y. (2014). Anti-IGF-1R monoclonal antibody inhibits the carcinogenicity activity of acquired trastuzumab-resistant SKOV3. Journal of ovarian research, 7(1), 103.
WB
Figure 2 WB analysis of IGF-1R in SKOV3 cells.
IGF-1R-positive SKOV3 cell preparation by eukaryotic transfection with pCMV6-IGF-1R plasmid.
Wang, W., Zhang, Y., Lv, M., Feng, J., Peng, H., Geng, J., ... & Ma, Y. (2014). Anti-IGF-1R monoclonal antibody inhibits the carcinogenicity activity of acquired trastuzumab-resistant SKOV3. Journal of ovarian research, 7(1), 103.
Specifications
- Immunogen
- Soluble extracellular domain of IGF-IR.
- Host Species
- Human
- Type
- Human antibody
- Specificity
- Human
- Species Reactivity
- Marmoset monkey, Cynomolgus monkey, Human
- Clone
- 1A
- Applications
- FC, WB
- Related Disease
- Tumor, Cancer
Applications
- Application Notes
- The IGF1R antibody has been reported in applications of Western Blot, Flow Cytometry.FC:Cells were collected and stained with appropriate PE conjugated antibodies against membrane markers. For each sample, data from approximately 15,000 cells were analyzed using a BD-FACStar™ instrument. Data analysis (the percentage and intensity of stained cells, etc.) was performed on a FACS Calibur flow cytometer using the BD CellQuest™ program. WB:The samples were electrophoretically separated on SDS-PAGE and transferred to NC membrane. The membranes were blocked with 5% non-fat dry milk dissolved in TBST (10 mM Tris HCl, 150 mM NaCl containing 0.05% Tween 20, pH 7.4) for 1 hour before probing overnight at 4°C with the appropriate primary antibody (IGF-1R). In the second day, after washed with TBST three times, the membranes were incubated with HRP-conjugated secondary antibody for 1 hour at room temperature.
Target
- Alternative Names
- IGF1R; insulin-like growth factor 1 receptor; IGFR; CD221; IGFIR; JTK13; IGF-I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2; insulin-like growth factor I receptor
- Gene ID
- 3480
- UniProt ID
- P08069
Related Resources
Insulin Signaling Pathway
Endocrine Resistance
Type I Diabetes Mellitus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-091 | Recombinant Anti-human IGF1R VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
| TAB-096ZJ | Anti-Human IGF-1R Single Domain Antibody (TAB-096ZJ), Research Grade Biosimilar | ELISA, IHC, IF, WB | Single domain antibody |
| HPAB-1545-FY | Recombinant Llama Anti-IGF1R Single Domain Antibody (HPAB-1545-FY) | WB, ELISA | Llama VHH |
| HPAB-1546-FY | Recombinant Llama Anti-IGF1R Single Domain Antibody (HPAB-1546-FY) | WB, ELISA | Llama VHH |
| HPAB-1547-FY | Recombinant Llama Anti-IGF1R Single Domain Antibody (HPAB-1547-FY) | WB, ELISA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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