Anti-IGF1R Recombinant Antibody (TAB-736) (CAT#: TAB-736)
Recombinant humanized (from mouse) antibody expressed in CHO binding to IGF1R. It is a humanized monoclonal antibody designed for the treatment of cancers.
Specific Inquiry
Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
SDS-PAGE
Figure 1 IGF1R Recombinant Antibody (TAB-736) in SDS-PAGE
SDS-PAGE analysis of TAB-736 in non-reduced (lane 1) and β-mercaptoethanol-reduced (lane 2) conditions. Gel stained for 30 minutes with Coomassie Blue. As a result of different β-mercaptoethanol-reduced proteins (Heavy chain and Light chain) migrate as about 50 kDa and 25 kDa, respectively. And non-reduced protein migrates as 130-180 kDa.
SEC-HPLC
Figure 2 IGF1R Recombinant Antibody (TAB-736) in HPLC
The purity of TAB-736 was greater than 95% as determined by SEC-HPLC.
Column: 3 µm, 7.8 x 300 nm
Mobile phase: 150 mM Sodium Phosphate Buffer, pH 7.0
Detection: UV 280 nm
Injection: 10 µl
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Humanized (from mouse)
- Type
- IgG1 - kappa
- Species Reactivity
- Human
- Applications
- FC, IP, ELISA, Neut, FuncS, IF, ICC, WB, Activ, Inhib
- MW
- 146.4 kDa
- Related Disease
- Solid tumors
Product Property
- Purity
- Purity >95% by SDS-PAGE.
- Storage
- Store at -20°C for long-term storage. Store at 2-8°C for up to one month. Avoid freeze/thaw cycles.
Applications
- Application Notes
- The IGF1R antibody has been reported in applications of FC, IP, ELISA, Neut, FuncS, IF, ICC, WB, Activ, Inhib.
Target
- Alternative Names
- dalotuzumab;1005389-60-5;MK-0646;MK0646;h7C10;IGF1R;insulin-like growth factor 1 receptor;CD221;IGFIR;IGFR;JTK13;MGC18216;IGF-I receptor;soluble IGF1R variant 1;soluble IGF1R variant 2;insulin-like growth factor I receptor;MGC142170;MGC142172;
- Gene ID
- 3480
- UniProt ID
- P08069
Related Resources
Please refer to Dalotuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Dalotuzumab.
Insulin Signaling Pathway
Endocrine Resistance
Type I Diabetes Mellitus
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-091 | Recombinant Anti-human IGF1R VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
| TAB-096ZJ | Anti-Human IGF-1R Single Domain Antibody (TAB-096ZJ), Research Grade Biosimilar | ELISA, IHC, IF, WB | Single domain antibody |
| HPAB-1545-FY | Recombinant Llama Anti-IGF1R Single Domain Antibody (HPAB-1545-FY) | WB, ELISA | Llama VHH |
| HPAB-1546-FY | Recombinant Llama Anti-IGF1R Single Domain Antibody (HPAB-1546-FY) | WB, ELISA | Llama VHH |
| HPAB-1547-FY | Recombinant Llama Anti-IGF1R Single Domain Antibody (HPAB-1547-FY) | WB, ELISA | Llama VHH |
Customer Reviews and Q&As
Customer Review
Q&As
Laura Brown
Ideal for IGF1R Research
Ideal for IGF1R Research
The Anti-IGF1R Therapeutic Antibody (dalotuzumab) has been excellent for our IGF1R research. Its specificity and sensitivity are top-notch, providing clear and reliable results. This antibody has significantly improved the accuracy of our experiments and saved us a lot of troubleshooting time.
03.Dec,23
Emily Lewis
Reliable in Immunoassays
Reliable in Immunoassays
We incorporated this antibody into our immunoassays, and it has been a great asset. The specificity for IGF1R is precise, allowing for accurate detection and analysis. The reliable performance has made it an invaluable tool in our lab.
09.Aug,22
John Carter
Consistent and Effective
Consistent and Effective
This antibody has proven to be consistent and effective in our various assays. The high-quality, reproducible results have significantly improved our experiments, making it a crucial part of our research toolkit. The strong affinity and specificity for IGF1R have been particularly beneficial.
26.Sep,21
Cite This Product
To accurately reference this product in your publication, please use the following citation information:
(Creative Biolabs Cat# TAB-736, RRID: AB_3111996)
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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