A*02:01/Human BIR (RLQEERTCKV) MHC Pentamer (CAT#: MHC-YF333)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed BIR-derived peptide of RLQEERTCKV sequence and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human pancreas
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in a subset of cells in islets of Langerhans.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48891/ihc_selected.jpg
(Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in a subset of cells in islets of Langerhans.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48891/ihc_selected.jpg
Figure 2 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48891/121831_A_7_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48891/121831_A_7_4.jpg
Figure 3 Pancreas
(Pancreatic endocrine cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48891/121831_A_2_3.jpg
(Pancreatic endocrine cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48891/121831_A_2_3.jpg
Figure 4 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48891/121831_A_5_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/48891/121831_A_5_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (Daudi, HEK93, MCF7, SCLC-21H, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000187486-KCNJ11
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000187486-KCNJ11
Specifications
- Allele
- A*02:01
- Class
- Class I
- Antigen
- BIR
- Antigen Species
- Human
- Peptide
- RLQEERTCKV
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2009]
- Alternative Names
- Potassium Voltage-Gated Channel Subfamily J Member 11; Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11; Potassium Channel, Inwardly Rectifying Subfamily J Member 11; Inward Rectifier K(+) Channel Kir6.2; IKATP; Inwardly-Rectifying Potassium Channel Subfamily J Member 11; Inwardly Rectifing Potassium Channel Subfamily J Member 11; Potassium Channel Inwardly Rectifing Subfamily J Member 11; ATP-Sensitive Inward Rectifier Potassium Channel 11;
- Gene ID
- 3767
- UniProt ID
- Q14654
Downloads
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See other products for "KCNJ11"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1996z | Recombinant Anti-Human KCNJ11 Antibody | WB, IHC, FuncS | IgG |
| MOB-2302CT | Recombinant Mouse anti-Human KCNJ11 Monoclonal antibody (N323A/31) | WB |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1996z-F(E) | Recombinant Anti-Human KCNJ11 Antibody Fab Fragment | ELISA, Nert, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1996z-S(P) | Recombinant Anti-Human KCNJ11 Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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