A*02:01/Human CAMEL (LMAQEALAFL) MHC Pentamer (CAT#: MHC-YF352)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed CAMEL-derived peptide of LMAQEALAFL sequence covering 2-11 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
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MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line K-562
(Immunofluorescent staining of human cell line K-562 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71467/1854_C4_1_selected.jpg
(Immunofluorescent staining of human cell line K-562 shows localization to nucleoplasm & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71467/1854_C4_1_selected.jpg
Figure 2 IF staining of human cell line K-562
(Immunofluorescent staining of human cell line K-562 shows localization to nucleoplasm, nuclear bodies & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76586/1854_F5_1_selected.jpg
(Immunofluorescent staining of human cell line K-562 shows localization to nucleoplasm, nuclear bodies & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/76586/1854_F5_1_selected.jpg
Figure 3 Colon
(Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71467/156342_A_9_3.jpg
(Glandular cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71467/156342_A_9_3.jpg
Figure 4 Kidney
(Cells in tubules Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71467/156342_A_9_5.jpg
(Cells in tubules Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71467/156342_A_9_5.jpg
Figure 5 High expression in testis
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: Low Intensity: Weak Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71467/156342_A_5_6.jpg
(Elongated or late spermatids Staining: Medium Intensity: Moderate Quantity:>75% Leydig cells Staining: Low Intensity: Weak Quantity:>75% Pachytene spermatocytes Staining: Medium Intensity: Moderate Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Round or early spermatids Staining: Medium Intensity: Moderate Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/71467/156342_A_5_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (GAMG, K-562, OE19, RPMI-8226, SK-BR-3, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000126890-CTAG2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000126890-CTAG2
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- CAMEL
- Antigen Species
- Human
- Peptide
- LMAQEALAFL
- Range
- 2-11
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Alternative Names
- Cancer/Testis Antigen 2; Autoimmunogenic Cancer/Testis Antigen NY-ESO-2; Cancer/Testis Antigen Family 6, Member 2a; Cancer/Testis Antigen Family 6, Member 2b; CTL-Recognized Antigen On Melanoma; Cancer/Testis Antigen 6.2; L Antigen Family Member 1; LAGE-1a Protein; LAGE-1;
- Gene ID
- 30848
- UniProt ID
- O75638
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