A*02:01/Human MG50 (LLLEAVPAV) MHC Pentamer (CAT#: MHC-YF555)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed MG50-derived peptide of LLLEAVPAV sequence covering 69-77 and A*02:01 molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
Specific Inquiry
Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IHC staining of human skin
(Immunohistochemical staining of human skin shows positivity in fibroblasts and extra cellular deposits.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12375/29401_B_7_1_selected.jpg
(Immunohistochemical staining of human skin shows positivity in fibroblasts and extra cellular deposits.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12375/29401_B_7_1_selected.jpg
Figure 2 Cerebral cortex
(Endothelial cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glial cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12375/29401_B_9_5.jpg
(Endothelial cells
Staining: Low
Intensity: Weak
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glial cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12375/29401_B_9_5.jpg
Figure 3 Colon
(Peripheral nerve/ganglion
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12375/29401_A_7_3.jpg
(Peripheral nerve/ganglion
Staining: Low
Intensity: Weak
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12375/29401_A_7_3.jpg
Figure 4 Urinary bladder
(Urothelial cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12375/29401_A_4_5.jpg
(Urothelial cells
Staining: Low
Intensity: Moderate
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12375/29401_A_4_5.jpg
Figure 5 Testis
(Elongated or late spermatids
Staining: Low
Intensity: Moderate
Quantity: <25%
Leydig cells
Staining: Low
Intensity: Moderate
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12375/29401_A_5_6.jpg
(Elongated or late spermatids
Staining: Low
Intensity: Moderate
Quantity: <25%
Leydig cells
Staining: Low
Intensity: Moderate
Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/12375/29401_A_5_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (EFO-21)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130508-PXDN/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000130508-PXDN/subcellular
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- MG50
- Antigen Species
- Human
- Peptide
- LLLEAVPAV
- Range
- 69-77
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a heme-containing peroxidase that is secreted into the extracellular matrix. It is involved in extracellular matrix formation, and may function in the physiological and pathological fibrogenic response in fibrotic kidney. Mutations in this gene cause corneal opacification and other ocular anomalies, and also microphthalmia and anterior segment dysgenesis.
- Alternative Names
- PXN; VPO; MG50; PRG2; ASGD7; COPOA; D2S448; D2S448E
- Gene ID
- 7837
- UniProt ID
- Q92626
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1728CT | Recombinant Mouse anti-Human PXDN Monoclonal antibody (2C11) | ELISA, WB |
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