A*02:01/Human PAX3/FKHR (QLMAFNHLI) MHC Pentamer (CAT#: MHC-YF659)

• Allele
• A*02:01

• Class
• Class I

• MHC Species
• Human

• Antigen
• PAX3/FKHR

• Antigen Species
• Human

• Peptide
• QLMAFNHLI

• Range
• 135-143

• Conjugate
• Unlabeled, Biotin, R-PE, APC

• Application
• FCM

• Antigen Introduction
• This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2;13)(q35;q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini. [provided by RefSeq, Jul 2008]

• Alternative Names
• Paired Box 3; HUP2; Paired Box Gene 3 (Waardenburg Syndrome 1); Transcriptional Factor PAX3; Paired Box Homeotic Gene 3; Paired Box Protein Pax-3; Paired Domain Gene HuP2;

• Gene ID
• 5077

• UniProt ID
• P23760

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