Human Anti-EPCAM Recombinant Antibody (clone 323/A3) (CAT#: FAMAB-0130CQ)
This product is a recombinant human antibody clone 323/A3, which specifically binds to EGP-2.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
SPR
Figure 1 Kinetic measurements using SPR in a BlAcore.
Sensorgrams showing association and dissociation of different anti-EGP-2 antibodies and antibody fragments: (A) whole antibodies (1, 17-1A; 2, chimeric 17-1A; 3, 323/A3; 4, MOC-31; 5, Bis-1) and (B) antibody fragments (1, MOC-31 scFv; 2, MOC-161 scFv) to the antigen coated to the surface of a sensor chip. Association starts at t = 130 s; dissociation starts at t = 310 s
Roovers, R. C., Henderikx, P., Helfrich, W., Van Der Linden, E., Reurs, A., De Bruine, A. P., ... & Hoogenboom, H. R. (1998). High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting. British journal of cancer, 78(11), 1407.
Specifications
- Immunogen
- Epithelial glycoprotein-2
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric (mouse/human) IgG
- Specificity
- Human EPCAM
- Species Reactivity
- Human
- Clone
- 323/A3
- Applications
- ELISA, IHC, FC
- Related Disease
- Cancers such as breast cancer, colorectal cancer, gastric cancer, lung cancer, and prostate cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Surface Plasmon Resonance.
Target
- Alternative Names
- Epithelial Cell Adhesion Molecule; Tumor-Associated Calcium Signal Transducer 1; Major Gastrointestinal Tumor-Associated Protein GA733-2; Adenocarcinoma-Associated Antigen; Cell Surface Glycoprotein Trop-1; Epithelial Glycoprotein 314; TACSTD1; EGP314; MIC18; TROP1; M4S1; KSA; Membrane Component, Chromosome 4, Surface Marker (35kD Glycoprotein); Antigen Identified By Monoclonal Antibody AUA1; Human Epithelial Glycoprotein-2; Epithelial Cell Surface Antigen; Epithelial Glycoprotein; KS 1/4 Antigen; CD326 Antigen; GA733-2; HEGP314; HNPCC8; Ep-CAM; DIAR5; EGP-2; EGP40; KS1/4; MK-1; M1S2; ESA; EGP
- Gene ID
- 4072
- UniProt ID
- P16422
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Biparatopic Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1093z | Mouse Anti-EPCAM Recombinant Antibody (clone 41D5) | WB, FC, IHC, IP, FuncS | Mouse IgG1, κ |
| MOB-074LC | Human Anti-EPCAM Recombinant Antibody (clone ING-1) | ELISA, FuncS | Humanized IgG1, κ |
| HPAB-0163CQ | Human Anti-EPCAM Recombinant Antibody (clone HuMAB UBS-54) | ELISA, FC, FuncS | Human IgG1 |
| HPAB-2219LY | Human Anti-EPCAM Recombinant Antibody (HPAB-2219LY) | ELISA | Human IgG |
| HPAB-2220LY | Human Anti-EPCAM Recombinant Antibody (HPAB-2220LY) | ELISA | Human IgG |
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For Research Use Only. Not For Clinical Use.
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