This product is a recombinant mouse antibody clone MOC-161, which specifically binds to EGP-2.
Figure 1 Kinetic measurements using SPR in a BlAcore.
Sensorgrams showing association and dissociation of different anti-EGP-2 antibodies and antibody fragments: (A) whole antibodies (1, 17-1A; 2, chimeric 17-1A; 3, 323/A3; 4, MOC-31; 5, Bis-1) and (B) antibody fragments (1, MOC-31 scFv; 2, MOC-161 scFv) to the antigen coated to the surface of a sensor chip. Association starts at t = 130 s; dissociation starts at t = 310 s
Roovers, R. C., Henderikx, P., Helfrich, W., Van Der Linden, E., Reurs, A., De Bruine, A. P., ... & Hoogenboom, H. R. (1998). High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting. British journal of cancer, 78(11), 1407.
Figure 2 Competition ELISA.
Binding of MOC-31 (solid bars) and of MOC-161 (hatched bars) scFv phage antibody to recombinant EGP-2 in the presence of (A) no competing antibody, (B) an excess of an irrelevant antibody (RFT5, an anti-CD25 hybridoma), (C) the MOC-31 whole antibody and (D) the MOC-1 61 whole antibody. OD values (y-axis) are corrected for background (which was approximately 0.08)
Roovers, R. C., Henderikx, P., Helfrich, W., Van Der Linden, E., Reurs, A., De Bruine, A. P., ... & Hoogenboom, H. R. (1998). High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting. British journal of cancer, 78(11), 1407.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-213 | Humanized Anti-EPCAM Recombinant Antibody (clone Tucotuzumab) | WB, Neut, ELISA, IF, IP, FuncS, FC | Humanized (from mouse) IgG1 |
TAB-235CL | Human Anti-Human EPCAM Recombinant Antibody (3622W94) | Cyt, FC | Antibody |
TAB-374MZ | Anti-Human EPCAM Recombinant Antibody (h12H8B) | FC, ELISA | Humanized antibody |
TAB-375MZ | Anti-Human EPCAM Recombinant Antibody (h12H8C) | FuncS, Inhib | Humanized antibody |
TAB-376MZ | Anti-Human EPCAM Recombinant Antibody (h2D11B) | Cyt, Inhib | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L013E | anti-EPCAM immunotoxin MOC31 (IgG)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L013D | anti-EPCAM immunotoxin MOC31 (IgG)-DT | Cytotoxicity assay, Functional assay | |
AGTO-L013G | anti-EPCAM immunotoxin MOC31 (IgG)-Gel | Cytotoxicity assay, Functional assay | |
AGTO-L013R | anti-EPCAM immunotoxin MOC31 (IgG)-RTA | Cytotoxicity assay, Functional assay | |
AGTO-L013O | anti-EPCAM immunotoxin MOC31 (IgG)-Bouganin | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-0531CL-F(E) | Anti-Human EPCAM Recombinant Antibody Fab Fragment (HE2) | ELISA, Inhib | |
TAB-363MZ-F(E) | Mouse Anti-EPCAM Recombinant Antibody; Fab Fragment (TAB-363MZ-F(E)) | Confocal, ELISA | Mouse Fab |
TAB-364MZ-F(E) | Mouse Anti-EPCAM Recombinant Antibody; Fab Fragment (TAB-364MZ-F(E)) | NIR (Near-infrared) fluorescence imaging, ELISA | Mouse Fab |
TAB-365MZ-F(E) | Mouse Anti-EPCAM Recombinant Antibody; Fab Fragment (TAB-365MZ-F(E)) | NIR (Near-infrared) fluorescence imaging, ELISA | Mouse Fab |
TAB-366MZ-F(E) | Mouse Anti-EPCAM Recombinant Antibody; Fab Fragment (TAB-366MZ-F(E)) | ELISA, WB, IHC | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-356MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (3-171) | FC, ELISA | Human antibody |
TAB-357MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (7-F17) | FC, ELISA | Human antibody |
TAB-358MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (12-C15) | FC, ELISA | Human antibody |
TAB-359MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (16-G5) | FC, ELISA | Human antibody |
TAB-360MZ-S(P) | Anti-Human EPCAM Recombinant Antibody scFv Fragment (17-C20) | FC, ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1163 | Hi-Affi™ Rabbit Anti-EPCAM Recombinant Antibody (clone DS1163AB) | IHC-P, WB, ICC, ICC, IF | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0129CQ | Human Anti-EPCAM Recombinant Antibody (clone 17-1A) | ELISA, IHC, FC | Chimeric (mouse/human) IgG |
FAMAB-0130CQ | Human Anti-EPCAM Recombinant Antibody (clone 323/A3) | ELISA, IHC, FC | Chimeric (mouse/human) IgG |
HPAB-0163CQ | Human Anti-EPCAM Recombinant Antibody (clone HuMAB UBS-54) | ELISA, FC, FuncS | Human IgG1 |
HPAB-2216LY | Human Anti-EPCAM Recombinant Antibody (HPAB-2216LY) | ELISA | Human IgG |
HPAB-2217LY | Human Anti-EPCAM Recombinant Antibody (HPAB-2217LY) | ELISA | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-106 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Adecatumumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
AFC-TAB-213 | Afuco™ Anti-EPCAM ADCC Recombinant Antibody (Tucotuzumab), ADCC Enhanced | Neut, ELISA, IF, IP, FuncS | ADCC enhanced antibody |
AFC-TAB-701 | Afuco™ Anti-EpCAM ADCC Recombinant Antibody (Edrecolomab), ADCC Enhanced | ELISA, IP, FC, FuncS, IF, Neut | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-2216LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2216LY-F(E)) | ELISA | Human Fab |
HPAB-2217LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2217LY-F(E)) | ELISA | Human Fab |
HPAB-2218LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2218LY-F(E)) | ELISA | Human Fab |
HPAB-2219LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2219LY-F(E)) | ELISA | Human Fab |
HPAB-2220LY-F(E) | Human Anti-EPCAM Recombinant Antibody; Fab Fragment (HPAB-2220LY-F(E)) | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-CN0031 | APC-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM | |
MHC-CN0032 | PE-H-2Db/Human Ep-CAM (CLVMKAEM) MHC Tetramer | FCM |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1520-FY-F(E) | Mouse Anti-EPCAM Recombinant Antibody (clone 2A9); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-1521-FY-F(E) | Mouse Anti-EPCAM Recombinant Antibody (clone FMU-EPCAM-4E4); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-1522-FY-F(E) | Mouse Anti-EPCAM Recombinant Antibody (clone FMU-EPCAM-4F6); scFv Fragment | ELISA, FC | Mouse scFv |
HPAB-2050-FY-S(P) | Human Anti-EpCAM Recombinant Antibody (clone K53); scFv Fragment | FC | Human scFv |
HPAB-2051-FY-S(P) | Human Anti-EpCAM Recombinant Antibody (clone 02-237); scFv Fragment | FC | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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