Mouse Anti-EPCAM Recombinant Antibody (clone MOC-161) (CAT#: FAMAB-0131CQ)
This product is a recombinant mouse antibody clone MOC-161, which specifically binds to EGP-2.
Specific Inquiry
SPR
Figure 1 Kinetic measurements using SPR in a BlAcore.
Sensorgrams showing association and dissociation of different anti-EGP-2 antibodies and antibody fragments: (A) whole antibodies (1, 17-1A; 2, chimeric 17-1A; 3, 323/A3; 4, MOC-31; 5, Bis-1) and (B) antibody fragments (1, MOC-31 scFv; 2, MOC-161 scFv) to the antigen coated to the surface of a sensor chip. Association starts at t = 130 s; dissociation starts at t = 310 s
Roovers, R. C., Henderikx, P., Helfrich, W., Van Der Linden, E., Reurs, A., De Bruine, A. P., ... & Hoogenboom, H. R. (1998). High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting. British journal of cancer, 78(11), 1407.
ELISA
Figure 2 Competition ELISA.
Binding of MOC-31 (solid bars) and of MOC-161 (hatched bars) scFv phage antibody to recombinant EGP-2 in the presence of (A) no competing antibody, (B) an excess of an irrelevant antibody (RFT5, an anti-CD25 hybridoma), (C) the MOC-31 whole antibody and (D) the MOC-1 61 whole antibody. OD values (y-axis) are corrected for background (which was approximately 0.08)
Roovers, R. C., Henderikx, P., Helfrich, W., Van Der Linden, E., Reurs, A., De Bruine, A. P., ... & Hoogenboom, H. R. (1998). High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting. British journal of cancer, 78(11), 1407.
Specifications
- Immunogen
- Epithelial glycoprotein-2
- Host Species
- Mouse
- Type
- Mouse IgG2a, κ
- Specificity
- Human EPCAM
- Species Reactivity
- Human
- Clone
- MOC-161
- Applications
- ELISA, IHC, FC
- Related Disease
- Cancers such as breast cancer, colorectal cancer, gastric cancer, lung cancer, and prostate cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Enzyme-linked Immunosorbent Assay and Surface Plasmon Resonance.
Target
- Alternative Names
- Epithelial Cell Adhesion Molecule; Tumor-Associated Calcium Signal Transducer 1; Major Gastrointestinal Tumor-Associated Protein GA733-2; Adenocarcinoma-Associated Antigen; Cell Surface Glycoprotein Trop-1; Epithelial Glycoprotein 314; TACSTD1; EGP314; MIC18; TROP1; M4S1; KSA; Membrane Component, Chromosome 4, Surface Marker (35kD Glycoprotein); Antigen Identified By Monoclonal Antibody AUA1; Human Epithelial Glycoprotein-2; Epithelial Cell Surface Antigen; Epithelial Glycoprotein; KS 1/4 Antigen; CD326 Antigen; GA733-2; HEGP314; HNPCC8; Ep-CAM; DIAR5; EGP-2; EGP40; KS1/4; MK-1; M1S2; ESA; EGP
- Gene ID
- 4072
- UniProt ID
- P16422
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-112-F(E) | Anti-Human EpCAM Recombinant Antibody Fab Fragment, 17-1A (Citatuzumab Bogatox) | Neut, ELISA, IF, IP, FuncS, FC, ICC | Fab - G1 - kappa |
| TAB-362MZ-F(E) | Anti-Human EPCAM Recombinant Antibody Fab Fragment (3622W94) | Confocal, ELISA | Humanized antibody |
| TAB-374MZ-F(E) | Anti-Human EPCAM Recombinant Antibody Fab Fragment (h12H8B) | FC, ELISA | Humanized antibody |
| TAB-375MZ-F(E) | Anti-Human EPCAM Recombinant Antibody Fab Fragment (h12H8C) | FC, ELISA | Humanized antibody |
| TAB-376MZ-F(E) | Anti-Human EPCAM Recombinant Antibody Fab Fragment (h2D11B) | FC, ELISA | Humanized antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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