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    Afuco™ Anti-IGF1R ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-209) (CAT#: AFC-TAB-209)

    This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IGF1 Receptor. It is a monoclonal antibody and an antineoplastic by Schering-Plough. It binds to CD221, the insulin-like growth factor 1 receptor.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
    Quantity :
    Conjugation :
    Fc Engineering :
    Modalities :
    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Normal Tissue
    Figure 1 Cerebral cortex
    Figure 1 Cerebral cortex
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Glial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Neuronal cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Neuropil
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_B_7_5.jpg
    Figure 2 Colon
    Figure 2 Colon
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Glandular cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_A_7_3.jpg
    Figure 3 Liver
    Figure 3 Liver
    (Cholangiocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Hepatocytes
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_A_8_4.jpg
    Figure 4 Kidney
    Figure 4 Kidney
    (Cells in glomeruli
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Cells in tubules
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_A_7_5.jpg
    Figure 5 Testis
    Figure 5 Testis
    (Cells in seminiferous ducts
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Leydig cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_A_6_6.jpg
    Figure 6 Heart muscle
    Figure 6 Heart muscle
    (Cardiomyocytes
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_B_5_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Non-germinal center cells
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10268/32662_A_7_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000140443-IGF1R

    Specifications

    • Immunogen
    • The details of the immunogen for this antibody are not available.
    • Host Species
    • Human
    • Derivation
    • Human
    • Type
    • ADCC enhanced antibody
    • Species Reactivity
    • Human
    • Applications
    • FuncS, IF, Neut, ELISA, FC, IP
    • Conjugate
    • Unconjugated
    • Generic Name
    • Robatumumab
    • Related Disease
    • Blood cancers

    Product Property

    • Purity
    • >95% by SDS-PAGE
    • Storage
    • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

    Target

    • Alternative Names
    • IGF1R; insulin-like growth factor 1 receptor; CD221; IGFIR; IGFR; JTK13; MGC18216; IGF-I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2; insulin-like growth factor I receptor;

    Related Resources

    • Biosimilar Overview
    • Related Signaling Pathways
    • Related Diseases
    Please refer to Robatumumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Robatumumab.

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Robatumumab"

    DrugMonitor™ Anti-Robatumumab Antibody (VS-1224-YC1028)
    Robatumumab is a monoclonal antibody with antineoplastic properties, studied in trials for conditions like osteosarcoma, Ewing's sarcoma, and peripheral neuroectodermal tumor. The DrugMonitor™ Anti-Robatumumab Antibody (VS-1224-YC1028) is an anti-drug antibody (ADA) against Robatumumab. This drug-based antibody is raised in mice immunized with the Robatumumab. The anti-Robatumumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Robatumumab in samples.

    See other products for "IGF1R"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Single Domain Antibodies Immunotoxins ADCC Enhanced Antibodies Humanized Antibodies Human Antibodies Chimeric Antibodies Mouse Antibodies Chicken IgY Antibodies Neutralizing Antibodies Blocking Antibodies Rabbit Monoclonal Antibodies Fab Antibodies IgG Antibodies Neuroscience Antibodies ScFv Antibodies Antibody Magnetic Beads ScFv-Fc Chimeras IHC Kits & Antibodies Extracellular Vesicle Antibodies Biparatopic Antibodies
    CAT Product Name Application Type
    NABL-091 Recombinant Anti-human IGF1R VHH Single Domain Antibody WB, ELISA, IHC, FC, FuncS Llama VHH
    TAB-096ZJ Anti-Human IGF-1R Single Domain Antibody (TAB-096ZJ), Research Grade Biosimilar ELISA, IHC, IF, WB Single domain antibody
    HPAB-1545-FY Recombinant Llama Anti-IGF1R Single Domain Antibody (HPAB-1545-FY) WB, ELISA Llama VHH
    HPAB-1546-FY Recombinant Llama Anti-IGF1R Single Domain Antibody (HPAB-1546-FY) WB, ELISA Llama VHH
    HPAB-1547-FY Recombinant Llama Anti-IGF1R Single Domain Antibody (HPAB-1547-FY) WB, ELISA Llama VHH

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