B*35:01/HIV Nef (VPLRPMTY) MHC Monomer

Name: B*35:01/HIV Nef (VPLRPMTY) MHC Monomer
SKU: MHC-YF179
Rating: 5 (1 reviews)

CAT#: MHC-YF179

This product is a MHC monomer of biotinylated peptide/MHC complex composed Nef-derived peptide of VPLRPMTY sequence covering 74-81 and B*35:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.

Specifications

Allele
B*35:01

Class
Class I

MHC Species
Human

Antigen
Nef

Antigen Species
HIV

Peptide
VPLRPMTY

Range
74-81

Conjugate
Biotin

Application
MHC Multimer

Target

Antigen Introduction
HIV-1 is the most common and pathogenic strain of the virus. Scientists divide HIV-1 into a major group (Group M) and two or more minor groups, namely Group N, O and possibly a group P. Each group is believed to represent an independent transmission of SIV into humans (but subtypes within a group are not). A total of 39 ORFs are found in all six possible reading frames (RFs) of HIV-1 complete genome sequence, but only a few of them are functional.

Alternative Names
HIV-1 Nef; Human immunodeficiency virus type-1 nef

Gene ID
156110

UniProt ID
P04601

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Datasheet

Datasheet - MHC-YF179.pdf

MSDS

MSDS - MHC-YF179.pdf

COA

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