DRB1*04:01/Human MAGE-A6 (LTQYFVQENYLEYRQVPG) MHC Monomer (CAT#: MHC-YF052)
This product is a MHC monomer of biotinylated peptide/MHC complex composed MAGE-A6-derived peptide of LTQYFVQENYLEYRQVPG sequence covering 246-263 and DRB1*04:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (GAMG, HMC-1, K-562, OE19, PC-3, SK-BR-3, U-266/70, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197172-MAGEA6
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000197172-MAGEA6
Specifications
- Allele
- DRB1*04:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- MAGE-A6
- Antigen Species
- Human
- Peptide
- LTQYFVQENYLEYRQVPG
- Range
- 246-263
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
- Alternative Names
- CT1.6; MAGE6; MAGE3B; MAGE-3b
- Gene ID
- 4105
- UniProt ID
- P43360
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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