For the longest possible shelf life, how should the monomer be kept?

To prevent degradation and for long-term binding efficacy, we recommend storing the monomer at -80°C.

When using this MHC Monomer, is it compatible with other immunological indicators?

There have not yet been any documented compatibility problems. In multiplex staining procedures with other immunological markers, it performs admirably.

What kinds of immunological responses unique to allergens can be identified with this monomer?

The monomer can help identify both Th1 and Th2 type immune responses specific to the Lol p1 allergen.

DRB1*04:01/Lolium perenne (Perennial ryegrass) Rye grass Lol p1 (APYHFDLSGHAFG) MHC Monomer (CAT#: MHC-YF018)

This product is a MHC monomer of biotinylated peptide/MHC complex composed Rye grass Lol p1-derived peptide of APYHFDLSGHAFG sequence covering 124-136 and DRB1*04:01 molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.

Specific Inquiry

Custom Production

MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

Peptide Sequence *:

Allele Requested *:

Antigen Species:

Antigen Molecule:

Sequence Position:

Form Requested *:

Conjugation *:

Size *:

Comments:

Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

We require custom production

Datasheet
MSDS
COA

Datasheet

MSDS

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Specifications

Allele
DRB1*04:01

Class
Class II

MHC Species
Human

Antigen
Rye grass Lol p1

Antigen Species
Lolium perenne (Perennial ryegrass)

Peptide
APYHFDLSGHAFG

Range
124-136

Conjugate
Biotin

Application
MHC Multimer

Target

Antigen Introduction
Causes an allergic reaction in human. Causes grass pollen allergy. Binds to IgE.

Alternative Names
Pollen allergen Lol p 1; Allergen Lol p I; Allergen R7; Allergen: Lol p 1

UniProt ID
P14946

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

Customer Reviews and Q&As

Customer Review Q&As

Consistent performance

A solid, reliable product. We've had consistent performance across multiple assays. Storage and handling guidelines were easy to follow, ensuring long-term usability.

Reproducible results

We saw substantial improvement in our epitope mapping studies using this monomer. The allergen-specific responses were clear and reproducible.

Quick shipping and excellent customer support

Quick shipping and excellent customer support. This monomer plays a crucial role in our ongoing projects. Its reliability is unmatched in the market.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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