What does the conjugation of this MHC monomer with biotin imply for its use?

The biotin-conjugation enables subsequent binding to streptavidin, facilitating its use in tetramer formation and enhancing its ability to stain and analyze specific T cell populations.

How should this MHC monomer be stored to maintain stability?

Store the monomer solution properly at recommended conditions, avoiding freeze/thaw cycles, to maintain its structural integrity and binding efficacy over extended periods.

H-2Db/ Adpgk Neoepitope (ASMTNMELM) MHC Monomer (CAT#: MHC-YF138)

This product is a MHC monomer of biotinylated peptide/MHC complex composed Adpgk Neoepitope-derived peptide of ASMTNMELM sequence and H-2Db molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.

Specific Inquiry

Custom Production

MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.

Peptide Sequence *:

Allele Requested *:

Antigen Species:

Antigen Molecule:

Sequence Position:

Form Requested *:

Conjugation *:

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Comments:

Disclaimer: Please note that the MHC reagents we offered have been produced with strict quality control (including gene sequencing, affinity purification, SDS-PAGE analysis, and verification of biotinylation), but many have not been confirmed to stain or activate specific T cells.

We require custom production

Datasheet
MSDS
COA

Datasheet

MSDS

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Specifications

Allele
H-2Db

Class
Class I

MHC Species
Mouse

Antigen
Adpgk Neoepitope

Peptide
ASMTNMELM

Conjugate
Biotin

Application
MHC Multimer

Target

Alternative Names
Adpgk Neoepitope

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

Customer Reviews and Q&As

Customer Review Q&As

High-Quality Conjugation

The biotin conjugation facilitates excellent binding and tetramer formation. This quality has enhanced our capability to effectively utilize it in cellular assays, aiding in the detailed analysis of T cell populations.

Stable and Effective

Once stored correctly, this MHC monomer maintains its efficacy over time, providing consistent results throughout repeated tests. Its stability reinforces our findings across different experimental setups.

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