H-2Kk/Human SMCY (TENSGKDI) MHC Pentamer (CAT#: MHC-YF714)
MHC pentamers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a MHC pentamer of peptide/MHC complex composed SMCY-derived peptide of TENSGKDI sequence covering 1332-1339 and H-2Kk molecule. The peptide/MHC pentamer provided here is unlabelled or fluorescent labelled, such as Biotin, R-PE, APC. All products are available in 50, 150 and 500 tests.
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Custom Production
MHC tetramer custom production provides a vital tool for researchers seeking to understand and manipulate T-cell immunity with exceptional precision. Please specify your requirements, including peptide sequence, MHC allele, and desired fluorophore etc. We will respond as soon as possible with a tailored solution.
We require custom production
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line Hep G2
(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoli fibrillar center.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49086/753_A8_1_selected.jpg
(Immunofluorescent staining of human cell line Hep G2 shows localization to nucleoli fibrillar center.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49086/753_A8_1_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (HEL, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012817-KDM5D
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000012817-KDM5D
Specifications
- Allele
- H-2Kk
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- SMCY
- Antigen Species
- Human
- Peptide
- TENSGKDI
- Range
- 1332-1339
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a protein containing zinc finger domains. A short peptide derived from this protein is a minor histocompatibility antigen which can lead to graft rejection of male donor cells in a female recipient. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
- Alternative Names
- Lysine Demethylase 5D; Jumonji, AT Rich Interactive Domain 1D (RBP2-Like); Jumonji/ARID Domain-Containing Protein 1D; Lysine (K)-Specific Demethylase 5D; Histocompatibility Y Antigen; Histone Demethylase JARID1D; Protein SmcY; JARID1D; SMCY; HYA; H-Y;
- Gene ID
- 8284
- UniProt ID
- Q9BY66
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