Recombinant Human Anti-Alpha-GalCer Soluble TCR (KIH) (VS-0622-YF5439) (CAT#: VS-0622-YF5439)

Human TCR recognizes Alpha-GalCer peptide in the context of CD1d. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.

Specific Inquiry
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  • Datasheet
  • MSDS
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Specifications

  • Host Species
  • Human
  • Target
  • Alpha-GalCer
  • MHC
  • CD1d
  • Type
  • Soluble TCR (KIH)
  • Related Disease
  • Cancer and autoimmune diseases
  • TCR Expression Strategy
  • KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).

Target

  • Alternative Names
  • α-GalCer; Alpha-Galactosylceramide

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Reliable Research Tool
This product has proven its reliability across multiple trials, consistently offering accurate readings of Alpha-GalCer engagement with iNKT cells. Its reliable performance has made it a staple in our lab for ongoing projects focusing on autoimmune disorder treatments.

Crucial for NKT Cell Studies
The Recombinant Human Anti-Alpha-GalCer Soluble TCR significantly advanced our study of iNKT cells. It precisely binds to the Alpha-GalCer-CD1d complex, facilitating detailed analysis of antigen recognition and response in autoimmune research models. The product's stability and specificity make it indispensable for our projects.

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For Research Use Only. Not For Clinical Use.

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