Recombinant Human Anti-Alpha-GalCer Soluble TCR (KIH) (VS-0622-YF5439)
CAT#: VS-0622-YF5439
Human TCR recognizes Alpha-GalCer peptide in the context of CD1d. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Specifications
- Host Species
- Human
- Target
- Alpha-GalCer
- MHC
- CD1d
- Type
- Soluble TCR (KIH)
- Related Disease
- Cancer and autoimmune diseases
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
- Alternative Names
- α-GalCer; Alpha-Galactosylceramide
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Reliable Research Tool
This product has proven its reliability across multiple trials, consistently offering accurate readings of Alpha-GalCer engagement with iNKT cells. Its reliable performance has made it a staple in our lab for ongoing projects focusing on autoimmune disorder treatments.
Crucial for NKT Cell Studies
The Recombinant Human Anti-Alpha-GalCer Soluble TCR significantly advanced our study of iNKT cells. It precisely binds to the Alpha-GalCer-CD1d complex, facilitating detailed analysis of antigen recognition and response in autoimmune research models. The product's stability and specificity make it indispensable for our projects.
Q&As
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What is Alpha-GalCer and its significance in research?
A: Alpha-GalCer, or α-Galactosylceramide, is a glycolipid known for activating iNKT cells. It plays a crucial role in research focused on cancer immunotherapies and autoimmune conditions due to its ability to modulate immune responses.
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Can I get this product with any conjugation options?
A: Yes, the Recombinant Human Anti-Alpha-GalCer Soluble TCR is available without conjugation and can be custom-ordered with various conjugates like PE, APC, Biotin, FITC, HRP, and others to fit specific assay requirements.
View the frequently asked questions answered by Creative Biolabs Support.
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