Human TCR (TCR052) recognizes fbpC peptide (QVPSASMGRDIKVQF) in the context of HLA-DRB1*03:01. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (TCR052). Please note that the activity is not guaranteed.

Specifications

Host Species
Human

Target
fbpC

Species Reactivity
Mycobacterium tuberculosis

Epitope
QVPSASMGRDIKVQF

MHC
HLA-DRB1*03:01

Clone
TCR052

Type
Soluble TCR (ZIP-Fos/ZIP-Jun)

TCR Expression Strategy
ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.

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