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    Recombinant Human Anti-HACL1 Soluble TCR (121) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF145)

    Human TCR (121) recognizes HACL1 peptide (QFADVIVLF) in the context of HLA-B*3501. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (121). Please note that the activity is not guaranteed.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line PC-3
    Figure 1 IF staining of human cell line PC-3
    (Immunofluorescent staining of human cell line PC-3 shows localization to vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/73760/1441_D4_3_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human duodenum
    Figure 2 IHC staining of human duodenum
    (Immunohistochemical staining of human duodenum shows moderate cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/35496/ihc_selected.jpg
    Figure 3 Colon
    Figure 3 Colon
    (Endothelial cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/35496/71277_A_7_3.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/35496/71277_A_7_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/35496/71277_A_8_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Cells in seminiferous ducts Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/35496/71277_A_5_6.jpg
    Figure 7 Lymph node
    Figure 7 Lymph node
    (Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/35496/71277_A_9_8.jpg
    RNA Expression
    Figure 8 RNA cell line category: Low cell line specificity
    Figure 8 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000131373-HACL1

    Specifications

    • Host Species
    • Human
    • Target
    • HACL1
    • Species Reactivity
    • Human
    • Epitope
    • QFADVIVLF
    • MHC
    • HLA-B*3501
    • Clone
    • 121
    • Type
    • Soluble TCR (ZIP-Fos/ZIP-Jun)
    • TCR Expression Strategy
    • ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.

    Target

    • Alternative Names
    • HACL1; HPCL; HPCL2; PHYH2; 2-HPCL; 2-hydroxyacyl-CoA lyase 1

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