Recombinant Human Anti-HTR1F Soluble TCR (JA12) (KIH) (CAT#: VS-0622-YF7250)
Human TCR (JA12) recognizes HTR1F peptide (VMPFSIVYI) in the context of HLA-A2. Soluble TCR is expressed with Knob-in-hole (KIH) strategy (scTCR-hIgG Knob, scTCR-hIgG Hole). Please note that the activity is not guaranteed.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human bronchus
(Immunohistochemical staining of human bronchus shows strong cytoplasmic positivity in respiratory epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/ihc_selected.jpg
(Immunohistochemical staining of human bronchus shows strong cytoplasmic positivity in respiratory epithelial cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/ihc_selected.jpg
Figure 2 Cerebral cortex
(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/15779_B_7_5.jpg
(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/15779_B_7_5.jpg
Figure 3 Bronchus
(Respiratory epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/15779_B_6_2.jpg
(Respiratory epithelial cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/15779_B_6_2.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/15779_A_9_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/15779_A_9_3.jpg
Figure 5 Liver
(Cholangiocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/15779_A_9_4.jpg
(Cholangiocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Hepatocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/15779_A_9_4.jpg
Figure 6 Kidney
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/15779_A_7_5.jpg
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/15779_A_7_5.jpg
Figure 7 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/15779_A_4_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5555/15779_A_4_6.jpg
Figure 8 RNA cell line category: Cell line enhanced (K-562, LHCN-M2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000179097-HTR1F
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000179097-HTR1F
Specifications
- Host Species
- Human
- Target
- HTR1F
- Species Reactivity
- Human
- Epitope
- VMPFSIVYI
- MHC
- HLA-A2
- Clone
- JA12
- Type
- Soluble TCR (KIH)
- TCR Expression Strategy
- KIH strategy: scTCR-human IgG Knob and scTCR-human IgG Hole can form heterodimer based on Knob-in-hole (KIH) strategy. The soluble TCR contains single chain TCR. With this KIH antibody production strategy, VL/VH will be replaced with Valpha-linker-Vbeta (single chain TCR).
Target
- Alternative Names
- 5-Hydroxytryptamine Receptor 1F; 5-Hydroxytryptamine (Serotonin) Receptor 1F, G Protein-Coupled; Serotonin Receptor 1F; 5-HT-1F; 5-HT1F; HTR1EL; 5-Hydroxytryptamine (Serotonin) Receptor 1F; 5HT6; MR77;
- Gene ID
- 3355
- UniProt ID
- P30939
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