Human TCR (Ob2F3) recognizes MMP19 peptide (RTQRIHFFKGDKVW) in the context of HLA-DRB1. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (Ob2F3). Please note that the activity is not guaranteed.

Gene Expression
Datasheet
MSDS
COA

Subcellular Location

Figure 1 IF staining of human cell line BJ
(Immunofluorescent staining of human cell line BJ shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70804/1332_D9_2_selected.jpg

RNA Expression

Figure 2 RNA cell line category: Cell line enriched (BEWO)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000123342-MMP19

Datasheet

MSDS

Certificate of Analysis Lookup
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Lot Number

Specifications

Host Species
Human

Target
MMP19

Species Reactivity
Oryctolagus cuniculus

Epitope
RTQRIHFFKGDKVW

MHC
HLA-DRB1

Clone
Ob2F3

Type
Soluble TCR (ZIP-Fos/ZIP-Jun)

Related Disease
Colorectal cancer

TCR Expression Strategy
ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.

Target

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