Recombinant Human Anti-SMARCD3 Soluble TCR (BD8) (ZIP-Fos/ZIP-Jun) (CAT#: VS-0622-YF2383)
Human TCR (BD8) recognizes SMARCD3 peptide (KLFEFLVHGV) in the context of HLA-A2. Soluble TCR expressed with ZIP-Fos/ZIP-Jun strategy (TRAV-TRAC partial-ZIP-Fos, TRBV-TRBC partial-ZIP-Jun) was validated to be able to bind pMHC in published references. The same expression strategy (ZIP-Fos/ZIP-Jun) is used to express this recombinant Human soluble TCR (BD8). Please note that the activity is not guaranteed.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression

Figure 1 IF staining of human cell line SH-SY5Y
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63955/if_selected.jpg
(Immunofluorescent staining of human cell line SH-SY5Y shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63955/if_selected.jpg

Figure 2 IF staining of human cell line HeLa
(Immunofluorescent staining of human cell line HeLa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65517/1277_F4_1_selected.jpg
(Immunofluorescent staining of human cell line HeLa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/65517/1277_F4_1_selected.jpg

Figure 3 IHC staining of human heart muscle
(Immunohistochemical staining of human heart muscle shows strong nuclear positivity in myocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63955/ihc_selected.jpg
(Immunohistochemical staining of human heart muscle shows strong nuclear positivity in myocytes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63955/ihc_selected.jpg

Figure 4 Cerebral cortex
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63955/147566_B_7_5.jpg
(Glial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63955/147566_B_7_5.jpg

Figure 5 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63955/147566_A_9_5.jpg
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63955/147566_A_9_5.jpg

Figure 6 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63955/147566_A_6_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/63955/147566_A_6_6.jpg

Figure 7 RNA cell line category: Cell line enhanced (AN3-CA)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000082014-SMARCD3
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000082014-SMARCD3
Specifications
- Host Species
- Human
- Target
- SMARCD3
- Species Reactivity
- Human
- Epitope
- KLFEFLVHGV
- MHC
- HLA-A2
- Clone
- BD8
- Type
- Soluble TCR (ZIP-Fos/ZIP-Jun)
- TCR Expression Strategy
- ZIP-Fos/ZIP-Jun strategy: the alpha and beta chain (without transmembrane and cytosolic region) can form heterodimer based on ZIP-Fox/ZIP-Jun. The soluble TCR contains variable regions and partial constant regions.
Target
- Alternative Names
- SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily D, Member 3; Mammalian Chromatin Remodeling Complex BRG1-Associated Factor 60C; 0 KDa BRG-1/Brm-Associated Factor Subunit C; SWI/SNF Complex 60 KDa Subunit C; BRG1-Associated Factor 60C; Swp73-Like Protein; BAF60C
- Gene ID
- 6604
- UniProt ID
- Q6STE5
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IHC Kits & Antibodies
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0325-XY2117 | Anti-SMARCD3 Immunohistochemistry Kit | IHC |
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