Recombinant Mouse Anti-CD40 Antibody (clone 4E4C6)

Name: Recombinant Mouse Anti-CD40 Antibody (clone 4E4C6)
SKU: VS3-FY289
Rating: 5 (1 reviews)

CAT#: VS3-FY289

This product is a recombinant mouse antibody that recognizes CD40 protein. This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Western Blot, Flow Cytometry, Immunohistochemistry.

Gene Expression

Normal Tissue Figure 1 Lymph node

Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72868/156401_A_8_8.jpg

Normal Tissue Figure 2 Tonsil

Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31567/156626_A_6_8.jpg

RNA Expression Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, EFO-21)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101017-CD40

❮

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Specifications

Host Species
Mouse

Type
Mouse IgG1

Specificity
CD40

Clone
4E4C6

Applications
Enzyme-linked Immunosorbent Assay, Western Blot, Flow Cytometry, Immunohistochemistry

Conjugate
Unconjugated

Product Property

Purity
>95%

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

Application Notes
This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Western Blot, Flow Cytometry, Immunohistochemistry.

Target

Alternative Names
CD40 Molecule; CD40 Molecule, TNF Receptor Superfamily Member 5; CD40L Receptor; TNFRSF5; CDW40; Bp50; Tumor Necrosis Factor Receptor Superfamily, Member 5

Gene ID
958

UniProt ID
P25942

Cellular Localization
Cell membrane, Membrane, Secreted

Protein Refseq
NP_001241.1; NP_001289682.1; NP_001309351.1

Function
Receptor for TNFSF5/CD40LG (PubMed:31331973).
Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).

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Related Diseases

Asthma

Systemic Lupus Erythematosus

Primary Immunodeficiency

Allograft Rejection

Autoimmune Thyroid Disease

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS3-FY289.pdf

MSDS

MSDS - VS3-FY289.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunohistochemistry (IHC)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

Secondary Antibody

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Isotype Control

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